TL;DR
Pretreatment with PEIV significantly mitigated effects of LPS-induced liver injury by regulating biochemical parameters, reducing oxidative stress and inflammation, and preserving liver architecture, suggesting its potential as a natural therapeutic agent for liver diseases.
Findings suggest that the hepatoprotective effect of HAEIB may be attributed to its antioxidant phytoconstituents and support its potential use as a natural hepatoprotective agent.
Findings demonstrate that the alcoholic extract of Panax ginseng possesses both preventive and therapeutic hepatoprotective properties against diclofenac-induced liver injury, likely mediated through its antioxidant and anti-inflammatory mechanisms.
It is demonstrated that the 50% methanolic extract of Curcuma pseudo-montana rhizomes possesses significant hepatoprotective activity against D-galactosamine-induced liver injury, supporting the traditional use of the plant in liver disorders.
CM significantly attenuates DOX-induced hepatotoxicity and nephrotoxicity, particularly at a dose of 250 mg/kg, and its protective effects are likely mediated through antioxidant, anti-inflammatory, and anti-apoptotic mechanisms.
The conclusion from this study can be helpful in the usage of AD as an adjuvant therapy that minimizes toxic effects of chemotherapy and improves treatment outcomes.
It is indicated that combining papaya, neem, and garlic extracts may provide greater hepatoprotection than administering the individual extracts against DEN-induced liver injury, and supports further mechanistic and preclinical evaluation of this polyherbal formulation before its potential therapeutic application in li...
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