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Author

O. Adewale

h-index 17 View on Semantic Scholar

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Review Open access Oct 2026

Targeting the IRE1α/XBP1 pathway in type 2 diabetes mellitus: from ER stress signaling to therapeutic opportunity

To respond to protein misfolding in the endoplasmic reticulum (ER), cells trigger the unfolded protein response (UPR) to re-establish proteostasis. However, unresolved UPR results in chronic ER stress, which is critical to the development and advancement of type 2 diabetes mellitus (T2DM), a multifactorial disease whos...

O. T. Obafemi, A. Ayeleso, B. E. Ekundayo et al. · 0 citations
Jul 2026

Antioxidant and anti-inflammatory effects of polyphenol-rich Illicium verum extract on lipopolysaccharide-induced liver injury in rats

Pretreatment with PEIV significantly mitigated effects of LPS-induced liver injury by regulating biochemical parameters, reducing oxidative stress and inflammation, and preserving liver architecture, suggesting its potential as a natural therapeutic agent for liver diseases.

S. Anadozie, A³ Maryam, Theophilus I. Ebe et al. · 0 citations

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