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neuroscience

128 papers

#neuroscience Preprint Open access Oct 2026

Many Brains, One Geometry: A Shared Visual-Semantic Space for Cross-Dataset fMRI Decoding

Visual decoding from fMRI is typically siloed by participant and experiment, obscuring whether heterogeneous neural measurements can be organized within a common computational geometry. Here we introduce BRAID-fMRI (Brain Representation Alignment across Individuals and Datasets), a shared CLIP-supervised decoding frame...

Moein Khajehnejad, Michelangelo Tronti, Forough Habibollahi et al. · 0 citations
#machine learning Preprint Open access Oct 2026

Structure alone supports efficient visual computation in the Drosophila visual system

Understanding the extent to which measured synaptic wiring determines computation remains a central challenge. Here, we couple the proofread adult Drosophila melanogaster connectome to an anatomically faithful model of its eye. Visual information is inputted in the eye model, then passed to the connectome, and finally...

Eudald Correig-Fraga, Roger Guimer\`a, Marta Sales-Pardo · 0 citations
#machine learning Preprint Open access Oct 2026

MovieSTAGE: Scene, Transition, and Global Encoding for Movie-fMRI ADHD Classification

Naturalistic movie-fMRI provides a shared, temporally structured probe of brain dynamics, yet predictive models commonly rely on whole-run functional connectivity (FC) or temporally generic representations that are not aligned with narrative events. We introduce MovieSTAGE (Scene, Transition, and Global Encoding), a mu...

Boseong Kim, Haejun Chung, Ikbeom Jang · 0 citations
#artificial intelligence Preprint Open access Oct 2026

Brain alignment of reasoning and action representations from vision-language and action models during naturalistic gameplay

Understanding how humans and artificial intelligence systems predict and plan by interacting with their environment is a fundamental challenge at the intersection of neuroscience and machine learning. Most brain-encoding studies focus on aligning artificial models with brain activity during language comprehension or pa...

Subba Reddy Oota, Anant Khandelwal, Khushbu Pahwa et al. · 0 citations
#artificial intelligence Preprint Open access Oct 2026

CircuitATLAS: Agentic reasoning over a systems neuroscience knowledge graph for target discovery in circuitopathies

Drug discovery for neurological disease has traditionally centered on the molecules altered by disease. But the molecules that cause pathology are not necessarily the best points from which to reverse it. Here, we ask which otherwise unaltered molecular control points can be engaged to restore pathological neural circu...

Gabriel Ocana-Santero, Marko Tvrdic · 0 citations
#artificial intelligence Preprint Open access Oct 2026

ReGraph: A Computational Account of Emergent Generalization in the "what" and "where" Dual Visual Streams

Where generalization capacity--the ability to extract context-invariant relational structures--first emerges remains a central question in AI and neuroscience. The foundation for this capacity lies upstream of the hippocampus, within the entorhinal cortex, where parallel pathways dissociate relational structure in the...

Hyewon Kang, Jungmin Lee, Ilgyu Lee et al. · 0 citations
#artificial intelligence Preprint Open access Oct 2026

Confidence-Ordering Reversal under Contextual Priors in Neural Decoding

Contextual priors improve neural-to-language decoding by reshaping candidate scores. However, confidence is read from the same reshaped scores, so the errors a prior leaves behind can become more confident with no change in accuracy to reveal it. We study how a prior shapes confidence in speech retrieval on MEG-MASC an...

Xinyu Zhang, Sichao Liu · 0 citations
#artificial intelligence Preprint Open access Oct 2026

Language-model ratings of depression reflect the rater more than the patient

Depression has no diagnostic blood test. Language models promise tireless, consistent assessment, but can accurate raters disagree about individuals? We pre-registered 880 language-model raters, crossing 11 open models with prompting and scoring choices, and applied them to 189 interviews against the eight-item Patient...

Baihan Lin · 0 citations
#machine learning Preprint Open access Oct 2026

CANDLE: Cortical Null-Space Decomposition for Noninvasive Brain Source Imaging

Electrophysiological source imaging (ESI) aims to estimate cortical source activity from noninvasive electrophysiological measurements such as electroencephalogram (EEG). However, ESI is fundamentally ill-posed because source activity is substantially higher-dimensional than sensor observations, resulting in non-unique...

Shuntaro Suzuki, Yuiga Wada, Komei Sugiura · 0 citations
#natural language process... Preprint Open access Oct 2026

Three tiers of computation in transformers and in brain architectures

Human language and logic abilities are computationally quantified within the well-studied grammar-automata hierarchy. We identify three hierarchical tiers and two corresponding transitions and show their correspondence to specific abilities in transformer-based language models (LMs). These emergent abilities have often...

E Graham, R Granger · 0 citations
#natural language process... Preprint Open access Oct 2026

COMPASS 2.0: psychometric representational similarity analysis distinguishes symptom structure from personal signal

Language models can score psychiatric questionnaires from speech, but agreement with self-report may reflect the questionnaire rather than the person. We introduce psychometric representational similarity analysis, a framework for comparing the structure of speech-derived scores, self-report, item wording and theory, a...

Baihan Lin · 0 citations
#machine learning Preprint Open access Oct 2026

Untrained CNNs Exceed Backpropagation in V1 Alignment at High Evaluation Resolution: A Systematic RSA Comparison of Four Learning Rules Against Human fMRI

Revised version (v4): noise ceiling replaced, analyses restricted to stimulus pairs presented in different fMRI runs, repaired evaluation of all five conditions. We compare four learning rules (backpropagation (BP), feedback alignment (FA), predictive coding (PC), and spike-timing-dependent plasticity (STDP)) in identi...

Nils Leutenegger · 0 citations

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