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protein folding

1,912 papers

#protein folding Open access Sep 2026

Integrative omics and field studies reveal the efficacy of PlantGuard, a next-generation biostimulant

This study presents the development and evaluation of a novel, natural plant oil-based biostimulant called PlantGuard, formulated from a blend of essential oil components and emulsifiers designed to enhance crop performance under field and controlled-environment hydroponics conditions. The biostimulant was applied to...

Walter Stünkel, T. Davtyan, A. Prazyan et al. · 0 citations
#protein folding Book Open access Sep 2026

THE EL-RAKHAWI THEORY OF BIO-QUANTUM INFORMATIONAL RESONANCE (BQIR) A UNIFIED FRAMEWORK FOR UNDERSTANDING LIFE AS A MACROSCOPIC QUANTUM INFORMATIONAL PHENOMENON

The El-Rakhawi Theory of Bio-Quantum Informational Resonance (BQIR) posits life as a macroscopic quantum informational phenomenon, not merely complex chemistry. Living systems exploit topological protection in cellular water networks to maintain room-temperature quantum coherence, enabling near-zero thermodynamic cost...

mohamed kamal arafa el-rakhawi · 0 citations
#protein folding Dataset Open access Sep 2026

Label-free quantitative proteomics of sham versus injured mouse cardiac tissue (PC1468)

This dataset contains label-free quantitative (LFQ) mass spectrometry proteomics of mouse cardiac tissue 4 weeks after sham surgery or myocardial infarction (MI) by coronary ligation. We analyzed 18 samples from 9 mice (4 sham, 5 MI), with each heart contributing myocardium above the infarct (remote) and below the infa...

Jonathan Cummings Schisler, Nicholas Gene Brown · 0 citations
#protein folding Dataset Open access Sep 2026

Refined Coordinate Structures and Pocket Analyses for Lysosomal Enzymes and Monogenic Metabolic Targets

v3.0.1 Correction Changelog: Restored GAA_splice_manifest-09-26-2026.json so that every file referenced by the MANIFEST is present in this record. No scientific content was changed. Dataset Title: Refined Coordinate Structures and Pocket Analyses for Lysosomal Enzymes and Monogenic Metabolic Targets (v3.0) Overview: Fu...

James Paul Trageser · 0 citations
#protein folding Dataset Open access Sep 2026

Refined Coordinate Structures and Pocket Analyses for Diabetes and Metabolic Disease Targets

v3.0.1 Correction Changelog: Restored INSR_splice_manifest-09-26-2026.json so that every file referenced by the MANIFEST is present in this record. No scientific content was changed. Dataset Title: Refined Coordinate Structures and Pocket Analyses for Diabetes and Metabolic Disease Targets (v3.0) Overview: Fully qualit...

James Paul Trageser · 0 citations
#protein folding Open access Sep 2026

De Novo Engineering of pH-Conditional, Cross-Species EGFR Binders via Higher-Dimensional ToposLang and Pharmacological Lattice Quantisation

Overview This record contains the manuscript, computational framework artifacts, candidate sequence datasets, and wet-lab experimental protocols for "De Novo Engineering of pH-Conditional, Cross-Species EGFR Binders via Higher-Dimensional ToposLang and Pharmacological Lattice Quantisation". Targeted therapeutics agains...

Elias Oulad Brahim · 0 citations
#protein folding Dataset Open access Sep 2026

Refined Coordinate Structures and Pocket Analyses for Endocrine Receptors and Viral Surface Antigens

Dataset Title: Refined Coordinate Structures and Pocket Analyses for Endocrine Receptors and Viral Surface Antigens (v3.0) Overview: Fully quality-controlled 3D structural models, geometric pocket analyses, DiffDock docking enrichment, and NIH NCBI cross-validated target records for 3 therapeutic targets in this diseas...

James Paul Trageser · 0 citations
#protein folding Open access Sep 2026

Peroxidase-Mediated Bioremediation of Lead and Zinc by Indigenous Bacterial Isolates: Enzymatic Characterization, Biosorption Kinetics, and Mechanistic Gene Expression Analysis

Background: Heavy metal contamination by lead (Pb) and zinc (Zn) poses a critical threat to environmental and public health. This study aimed to isolate and characterize indigenous metal-resistant bacteria from contaminated agricultural soil in Wasit Governorate, Iraq, and to establish a quantitative link between perox...

Duaa Rassol Muhsen, M. K. Mohammed · 0 citations
#protein folding Dataset Open access Sep 2026

Refined Coordinate Structures and Pocket Analyses for Oncology Targets

v3.0.1 Correction Changelog: Restored APC_splice_manifest-09-26-2026.json, AR_splice_manifest-09-26-2026.json so that every file referenced by the MANIFEST is present in this record. No scientific content was changed. Dataset Title: Refined Coordinate Structures and Pocket Analyses for Oncology Targets (v3.0) Overview:...

James Paul Trageser · 0 citations
#protein folding Open access Sep 2026

Regulation of Fused in Sarcoma Condensate Formation and Dissolution Using Butterfly-Shaped Gold Nanoparticles

A Biomolecular condensates, formed through liquid–liquid phase separation (LLPS), play a crucial role in organizing various cellular functions. Materials that can regulate condensate dynamics without genetic modification could provide new tools for controlling biomolecular organization. In this study, we explored butte...

Tomohiro Nobeyama, Keiji Kitamura, Ryo Kitahara et al. · 0 citations
#protein folding Dataset Open access Sep 2026

Refined Coordinate Structures and Pocket Analyses for Hematology and Coagulation Targets

Dataset Title: Refined Coordinate Structures and Pocket Analyses for Hematology and Coagulation Targets (v3.0) Overview: Fully quality-controlled 3D structural models, geometric pocket analyses, DiffDock docking enrichment, and NIH NCBI cross-validated target records for 3 therapeutic targets in this disease area: F8,...

James Paul Trageser · 0 citations
#protein folding Sep 2026

Discriminating Monomers and Fibrils of Amyloid‐ β 1–42 With Site‐Ordered Peptide‐QMFluors

ABSTRACT The detection of soluble amyloid‐ β (A β ), the most neurotoxic species in early Alzheimer's disease (AD), remains a major analytical challenge. Conventional probes are designed to target the β ‐sheet structures of mature fibrils and are thus blind to these transient, nonfibrillar species. Here, we introduce “...

Ruilong Dai, Jianfeng Dai, Chenxu Yan et al. · 0 citations

From tech blogs

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Google DeepMind Blog Sep 30, 2026

Introducing SynthID Bio

Proof of concept for watermarking AI-generated proteins while preserving biological function.

MIT News · Artificial Intelligence Aug 27, 2026

Looking beyond natural sequences

A new machine-learning framework aims to improve the success rate of computational protein design while moving away from results that reproduce sequences found in nature.

Google DeepMind Blog Nov 25, 2025

AlphaFold: Five years of impact

Explore how AlphaFold has accelerated science and fueled a global wave of biological discovery.

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