It is demonstrated that DVA exerts a dual therapeutic effect by restoring essential mitochondrial and metabolic pathways while simultaneously suppressing inflammation, oxidative stress, and cytoskeletal dysregulation in CKD.
This paper introduces a novel framework for quantum computing that integrates adaptive quantum state generation algorithms with the self-adaptive geometry of topology. The core idea is to combine the precision of quantum computation with the inherent flexibility of topological structures. We propose a method for dynami...
Jincheng Zhang· Zenodo (CERN European Organi...· 0 citations
This paper introduces an innovative framework for analyzing and optimizing fractal networks, leveraging the concept of 'Symmetry Metric' to guide network design. We propose a novel method for quantifying network structure using a mathematical definition of self-similarity and employing this metric to optimize network p...
Jincheng Zhang· Zenodo (CERN European Organi...· 0 citations
Psoriasis is a chronic inflammatory skin disorder marked by skin hyperproliferation and rapid inflammation. Effective therapies should be immunomodulatory, anti-inflammatory and antioxidant in nature. This study evaluates the therapeutic potential of grape seed extract (GSE) (Vitis vinifera L.) in managing psoriasis b...
T Vandanaraj, T Santhrani· Plant Science Today· 0 citations
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Quantum-driven constraint on complex systems aims to accelerate solution processes by dynamically adjusting constraint parameters. This paper explores the potential of quantum annealing and variational quantum eigensolver (VQE) to optimize these parameters. The core claim is to implement an algorithm that dynamically a...
Jincheng Zhang· Zenodo (CERN European Organi...· 0 citations
In this retrospective analysis, neoGFAP provided clearer incremental value than total GFAP for recovery-oriented monitoring, especially when late-window reassessment of patients who remained at risk for less-than-good recovery was required.
K.-K.-W. Wang, G. Cai, K. Boukholda et al.· medRxiv· 0 citations
Fluorescent indicators are indispensable imaging tools for visualizing the spatiotemporal dynamics of biological processes. Red fluorescent indicators are in particularly high demand because they offer compatibility with existing green fluorescent indicators or optogenetic tools, and longer wavelength fluorescence has...
Shosei Imai, Wen-Chao Zhu, Robert E. Campbell et al.· ACS Chemical Biology· 0 citations
This paper introduces a novel self-adaptive optimization algorithm designed for modeling biological molecules. Biological systems exhibit intricate and dynamic behaviors, making traditional optimization methods often inadequate. This algorithm addresses this limitation by incorporating a self-adjustment mechanism that...
Jincheng Zhang· Zenodo (CERN European Organi...· 0 citations
Vernonia calvoana (VC), a commonly used medicinal plant in West Africa, has been shown by our research team to inhibit the proliferation of OVCAR-3 ovarian cancer cells through mechanisms involving oxidative stress, DNA damage, and S-phase cell cycle arrest. The objective of the current study was to elucidate the intri...
Ariane M. Chitoh, Clément G. Yedjou, Ingrid K. Tchakoua et al.· International Journal of Mol...· 0 citations
Service members with traumatic brain injury are at approximately two- to four-fold higher risk of Alzheimer's disease or related dementias than those without such an injury, with risk increasing with injury severity. The amyloid/tau/neurodegeneration biomarker framework treats amyloid, tau, and neurodegeneration as ind...
W. E. Haskins, K.-K. Wang, G. Cai et al.· medRxiv· 0 citations
This preprint introduces the molecular and biochemical extension of The Bell TowerArchitecture. By taking the asymptotic limit (ε → 0) of the discrete lattice Z^3, we define acontinuous rigid field Φ(z) governed by Weierstrass infinite products and Mittag-Leffler expansions. This geometric framework replaces traditiona...
Silvio Gabbianelli· Zenodo (CERN European Organi...· 0 citations
Nitrogen-containing organic compounds (NOCs) are key characteristic components in particulate matter (PM) from household solid fuel combustion, yet their personal exposure and class-dependent toxicity remain poorly characterized. We compared size-resolved personal exposure to particulate nitrated phenols (NPs) and ni...
Rong Feng, Hong-Mei Xu, Zhen-Xing Shen et al.· Environmental Science &...· 0 citations
A new machine-learning framework aims to improve the success rate of computational protein design while moving away from results that reproduce sequences found in nature.
