Genomic Evidence Stability (GES) — Springer Revision Reproducibility Freeze This release freezes the reproducibility package supporting the revised GES chapter submitted to the edited volume Artificial Intelligence in Therapeutic Innovation. Included analyses January 2023 → January 2026 ClinVar temporal validation Froz...
Sanghati Basu· Zenodo (CERN European Organi...· 0 citations
Inherited mitochondrial cardiomyopathies arise from pathogenic variants that disrupt oxidative phosphorylation, mitochondrial DNA maintenance, cardiolipin biogenesis, or mitochondrial dynamics and quality control. Although the causative genes are diverse—mtDNA mutations, nuclear respiratory-chain and assembly factors,...
Findings place silkworm cryptochromes at a key interface between environmental sensing, circadian timing and seasonal developmental control, with potential implications for sericulture.
Daniel J. Brady, Federica Sandrelli· Frontiers in Physiology· 0 citations
Cis-regulatory elements (CREs) orchestrate the spatiotemporal precision of gene expression that underlies plant development, adaptation, and domestication. Decoding the cis-regulatory grammar of plant genomes remains a central challenge in modern biology, with profound implications for programmable crop engineering. He...
Li-Bin Zhang, Maoteng Li· Journal of Integrative Plant...· 0 citations
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This review provides a next-generation perspective on vermiremediation by integrating species-level physiology, gut microbiome functionality, molecular detoxification pathways, synthetic biology innovations, multi-omics insights, and artificial intelligence (AI)-driven modeling into a unified framework.
Inrikynti Mary Kharmawphlang, María Gómez-Brandón, Nazneen Hussain· Biodegradation· 0 citations
A rapid nanopore sequencing pipeline is highlighted, which is named NanoCutSight, to quantify the percentage of indels at a specific genomic locus and to identify the types of modifications generated.
Danny Bergeron, Véronique Gaudreault, Maxime Duval et al.· bioRxiv· 0 citations
The present study represents the first application of base editing in barley plants, using the EIF4E gene as an example, and two newly generated alleles led to resistance upon BaMMV inoculation without adverse effects on yield, proving this approach promising to generate new material for resistance breeding.
R. Hoffie, A. Habekuss, D. Perović et al.· bioRxiv· 0 citations
Infertility affects approximately one in six individuals worldwide and is a highly heterogeneous disorder resulting from the complex interplay of genetic, epigenetic, endocrine, environmental and lifestyle factors. Although numerous genes and molecular pathways involved in female and male infertility have been identifi...
Paul Barreau, C. Djari, J. de Vos et al.· Genes· 0 citations
PURPOSE OF REVIEW
To review advances from the past 18 months in allogeneic hematopoietic stem cell transplantation (HSCT) and autologous gene-modified stem cell transplantation for sickle cell disease (SCD), and to relate these developments to stem cell biology, conditioning and emerging prenatal strategies.
RECENT F...
Giula Mackina, Panicos Shangaris· Current opinion in hematolog...· 0 citations
The rapid development of CRISPR genome editing technologies has established a transformative paradigm within biomedical research, drug discovery, and gene therapy. Despite the robust nuclease activity and programmable targeting exhibited by these systems, the clinical translation of CRISPR-mediated therapeutics remai...
Li Du, Xiao-Feng Hua, Qianquan Ma et al.· Molecular Medicine· 0 citations
The nervous system relies on billions of neurons connected through trillions of synapses to support vital functions. Despite the importance of this synaptic network, cellular mechanisms dictating synapse formation during human neurodevelopment remain unclear. Long-distance trafficking by the microtubule motor KIF1A is...
Jayne Aiken, Carris Borland, Nicolas Marotta et al.· Journal of Cell Biology· 0 citations
Exploring how generative AI could make machine vision more accessible to businesses. The post GenEye in a Box: Making Machine Vision Something You Can Just Ask For appeared first on GPT-Lab.
