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1,414 papers
The first paired plastome and mitogenome of Galeola nudifolia Lour.
DNA repair outcomes at nicks and mismatches introduced by base editors at the PCSK9 and HBG loci in human embryos are evaluated, finding that unlike Cas9-induced DNA breaks, base editor-induced lesions are efficiently repaired.
This work presents a theoretical development program for a single-administration adeno-associated virus (AAV) gene therapy designed to treat chronic kidney disease (CKD) in the domestic cat. The approach centers on the delivery of an affinity-detuned variant of feline Apoptosis Inhibitor of Macrophage (m-fAIM), enginee...
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This work presents a theoretical development program for a single-administration adeno-associated virus (AAV) gene therapy designed to treat chronic kidney disease (CKD) in the domestic cat. The approach centers on the delivery of an affinity-detuned variant of feline Apoptosis Inhibitor of Macrophage (m-fAIM), enginee...
Artemisinin partial resistance (ART R ) in Plasmodium falciparum is mediated by Pfkelch13 mutations but has not emerged in West Africa. Using gene editing, we introduced four Pfkelch13 mutations into a recent Senegalese isolate, evaluating the receptivity of this genetic background to ART R using the ring-stage surviva...
This review critically updates the Pariza microbial enzyme safety evaluation decision tree, which has been used by industry since the turn of the century, to reflect current biotechnology tools and microbial safety assessment practices. The updated decision tree preserves the principle that enzyme safety depends primar...
Gene-editing technologies offer transformative potential for sustainable food production, yet acceptance by some consumers remains a concern. This study examines New Zealand consumers’ attitudes toward gene-edited foods and regulatory reform, applying the cognitive-affective personality system model to uncover the psyc...
A high-resolution spatial and temporal atlas of the postnatal mouse heart is generated by integrating single-nucleus RNA sequencing with image-based spatial transcriptomics, revealing dynamic cellular interactions, niche-specific signaling and transcriptional programs guiding cardiomyocyte maturation.
It is discovered that incorporating TriGalNAc-lipid into LNPs containing DSPE-PEG350 increased hepatic luciferase expression 4–6-fold over TriGalNAc-conjugated or unconjugated DMG-PEG2000 LNPs, and 60-fold over TriGalNAc-conjugated or unconjugated DSPE-PEG2000 LNPs in vivo.
Genomic Evidence Stability (GES) — Springer Revision Reproducibility Freeze This release freezes the reproducibility package supporting the revised GES chapter submitted to the edited volume Artificial Intelligence in Therapeutic Innovation. Included analyses January 2023 → January 2026 ClinVar temporal validation Froz...
<!-- release-title: v1.10.0: MCP --> wisp-science v1.10.0 v1.10.0 brings scientific MCP tools into Wisp's native Rust runtime. The bundled catalog provides 23 connectors and 247 tools across roughly 80 upstream databases, with browsable connector introductions and tool parameters. This release also improves first-time...
GPT-Lab
· gpt-lab.eu
Oct 8, 2026
Exploring how generative AI could make machine vision more accessible to businesses. The post GenEye in a Box: Making Machine Vision Something You Can Just Ask For appeared first on GPT-Lab.
A Blog post by Ai2 on Hugging Face
A Blog post by ServiceNow-AI on Hugging Face
“InstructMesh” can generate designs for everyday objects that are easy to edit and fabricate for both experts and newcomers to 3D modeling.
Proof of concept for watermarking AI-generated proteins while preserving biological function.
Algorithms & Theory
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