Comparative visualization of bacterial genome structure is an important component of microbial genomics, enabling the inspection of genome conservation, rearrangements, inversions, insertions and deletions, and large-scale differences in gene organization. I present bactiviz, a lightweight command-line tool for generat...
Adeno associated viral (AAV) delivery of CRISPR-Cas9 enables efficient, targeted hepatic gene disruption composed of both small insertions and deletions (INDELs) and larger DNA structural variants (DNA-SVs), which are difficult to quantify. Here, we present a protocol for quantifying AAV-CRISPR-mediated gene editing in...
K. Jarrett, Rodrigo Baltazar-Nunez, Chloe Anne Borja et al.· STAR Protocols· 0 citations
Reach audiences
Advertise in front of researchers, engineers, and readers.
Tourmaline v2.2.0 This release adds the tax-credit step: a fourth, optional workflow step that benchmarks reference databases and taxonomic classifiers, based on code from Bokulich et al. 2018. Bokulich NA, Kaehler BD, Rideout JR, Dillon M, Bolyen E, Knight R, Huttley GA, Caporaso JG. Optimizing taxonomic classificatio...
Luke Thompson, Katherine Silliman, Luke Thompson et al.· Zenodo (CERN European Organi...· 0 citations
Gilts reaching puberty early have greater lifetime productivity but 10-20% are acyclic before first breeding, presenting a major management challenge. Puberty is a complex maturational process, involving molecular and cellular events that are influenced by the environment, nutrition, and genetics. Initiation of puber...
C. A. Lents, H. Wijesena, D. Nonneman et al.· Journal of Animal Science· 0 citations
First-in-human studies involving gene transfer or genome editing give rise to complex uncertainties. There is a broad acknowledgment that the current scientific guidelines should be supplemented with ethical guidance, particularly with regard to decisions about whether to initiate such trials. As a first step toward th...
Hélène Nobile, Marcel Mertz· Research Ethics· 0 citations
Natural mutations in the prolactin receptor gene (PRLR) result in slick hair phenotype and improved thermoregulation. Gene-editing technologies allow the introduction of novel variants into PRLR, providing a strategy to rapidly incorporate slick phenotype into cattle populations. The objective of this study was to ev...
R. Oliveira, R. Cooke, T. Minela et al.· Journal of Animal Science· 0 citations
Tomato production is increasingly threatened by the growing occurrence and severity of combined drought and high-temperature stress. Although the individual effects of high temperature and drought stress on tomato growth, physiology, and productivity have been widely investigated, their combined occurrence exerts more...
P. R. Athmika, A. Senthil, M. Djanaguiraman et al.· Plant Science Today· 0 citations
What's Changed ZFIN-10433: fetch the PANTHER classifications over HTTPS by @cmpich in https://github.com/ZFIN/zfin/pull/1964 ZFIN-10389: Update journals with ISSNs by @cmpich in https://github.com/ZFIN/zfin/pull/1963 ZFIN-10344 Follow-up: Add parameters to make the switchover easier by @rtaylorzfin in https://github.co...
Christian Pich, Ryan Taylor, zfinryanm et al.· Zenodo (CERN European Organi...· 0 citations
The reproduction workflow and the archived intermediate results for the paper. Everything needed to rebuild the manuscript's tables is here: the code is a snapshot of the trimmed reproduction repository, and the bundles hold the computed intermediates, so a reader does not have to re-derive them. Reproducing from the r...
Chand Sahil Mansuri, Joel Zachariah, Sadamori Kojaku· Zenodo (CERN European Organi...· 0 citations
Genome editing in avian systems has largely relied on plasmid-based CRISPR systems and antibiotic selection to achieve successful editing. However, plasmid delivery can result in prolonged nuclease expression and potential unintended DNA integration. In addition, selection-based enrichment may mask the intrinsic geno...
Sydney G. Bingham, Jin Lee Kim, Kiho Lee et al.· Journal of Animal Science· 0 citations
Exploring how generative AI could make machine vision more accessible to businesses. The post GenEye in a Box: Making Machine Vision Something You Can Just Ask For appeared first on GPT-Lab.