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gene editing

1,434 papers

#gene editing Open access Aug 2026

Genetic transformation and CRISPR/Cas12a-mediated gene editing of European beech (Fagus sylvatica L.) employing a transient protoplast system

A new protoplast-based platform enables transient transformation and proof-of-concept CRISPR/Cas12a-mediated genome editing in European beech, a key but recalcitrant forest tree species.

Virginia Zahn, Alice-Jeannine Sievers, B. Kersten et al. · 0 citations
#gene editing Review Open access Aug 2026

Recent applications of CRISPR-Cas systems in animal models of human cardiovascular disease: Review article

A review of studies in which the creation of a CRISPR-Cas9 animal model has been used to find genetic drivers and develop therapies across 4 CVD domains shows the vast range of gene editing applications and the value of models that parallel human genetic pathophysiology for specific disease processes.

J. Longmire, Harrison Smith-Jaoudi, Eesha Balar et al. · 0 citations
#gene editing Open access Aug 2026

Viperin as a putative antiviral effector in rainbow trout (Oncorhynchus mykiss) cells identified by CRISPR-Cas9 functional analysis following exposure to inactivated viral hemorrhagic septicemia virus

It is demonstrated that viperin plays a central role in coordinating antiviral responses in rainbow trout macrophages and is essential for proper activation of classical IFN–ISG pathways.

Mariana Vaz, A. Florea, G. E. Themudo et al. · 0 citations
#gene editing Open access Aug 2026

The gene homologous to OsCd1, designated as ABNORMAL SHOOT IN YOUTH (OsASY), functions as a cadmium influx transporter in rice.

Preliminary evidence indicates that targeted editing of OsASY offers a promising strategy to reduce grain Cd content without adversely affecting major agronomic traits or yield, highlighting its potential as a molecular target for breeding low-Cd-accumulating rice varieties.

Chun-Yan Tu, Wei Huang, Dao-Bo Wang et al. · 0 citations
#gene editing Aug 2026

TAAR1 as a Target for Addiction Therapy.

Overall, the existing findings support TAAR1 as a therapeutic target for treatment of substance use disorders, however, translating these findings into effective human pharmacotherapies requires navigating ligand-specific effects and pharmacokinetic demands and defining the role of human TAAR1 genetic diversity in ther...

Samantha M. Rios, S. Shabani, T. J. Phillips · 0 citations
#gene editing Review Aug 2026

[Application of genetic engineering technology in heavy metal bioremediation].

This paper focuses on the heterologous expression of functional genes via transgenic technology and explores the potential of gene editing technologies for heavy metal remediation, thereby offering a reference for future environmental remediation efforts and the development of related processes.

Kaiyang Zheng, Yeting Weng, Ran Zhao · 0 citations
#gene editing Review Open access Aug 2026

A Comprehensive Review of Starches From Diverse Millets: Composition, Structure, Functionality, and Strategies for Genetic Improvement.

Millets are a diverse group of underutilized C4 cereals with high photosynthetic efficiency and resilience to marginal environments; however, the functional and nutritional potential of their starches remains largely untapped. This review provided a systematic summary of current research in millet starches, covering ex...

Raheela Amin, Huabing Lu, Jing Yu et al. · 0 citations
#gene editing Open access Aug 2026

Phenotypic, hydroponic performance assessment, and expression profiling of triple knockout negative regulator genes in rice (Oryza sativa L.)

Rice is one of the most significant crops consumed daily by individuals. Enhancing and biofortifying rice to augment its nutritional value is a promising strategy for improving public health and tackling the widespread issue of micronutrient deficiencies. This study primarily attempted to evaluate the developed Cas9-fr...

Khaled Fathy, Tanushri Kaul, Pawan K. Agrawal · 0 citations
#gene editing Open access Aug 2026

Multiple shoot induction from embryonic axes of mature seeds supports a novel regeneration platform for biolistic DNA delivery in Theobroma cacao L.

A novel embryonic axis-based regeneration system enables rapid shoot recovery, rooting, and biolistic gene delivery in cacao, substantially shortening the timeline for plant transformation.

Suzam L. da S. Pereira, Grazielle da M. Alcântara, Gláucia C. B. Silva et al. · 0 citations
#gene editing Open access Aug 2026

Modulation of the sensitivity to ruxolitinib-mediated JAK2 inhibition by mutationally activated SHP2 exhibits cell context dependency in pre-clinical models of myeloproliferative neoplasms

The identification and characterization of an activating point mutation of SHP2 (encoded by the PTPN11 gene), SHP2-F71L, in UKE1 cells is reported, suggesting activating PTPN11 mutations have the potential to desensitize the effects of JAK2 inhibition therapy in patients undergoing therapy and may be dependent on unkno...

Tegan M. Rowsell, G. Pandey, Lucia Mazzacurati et al. · 0 citations

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Google DeepMind Blog Sep 30, 2026

Introducing SynthID Bio

Proof of concept for watermarking AI-generated proteins while preserving biological function.

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