The purpose of the study is to provide a scientific substantiation and experimental evaluation of the effectiveness of Sub–Pro probiotic application to increase productivity, improve feed conversion and biological usefulness of meat from Cobb 500 cross broiler chickens in industrial cultivation. The experiment was conducted on 100 birds of one day-old broiler chickens, divided into control and experimental groups (50 heads each). The birds of the experimental group received a probiotic solution at a concentration of 10 g per 1 ton of water for 42 days. The microbial background of the chyme of the cecum was assessed by the method of limiting dilutions at inoculation on selective media. The digestibility of feed nutrients was determined based on the results of a balance experiment. The chemical, amino acid composition and veterinary and sanitary examination of muscle tissue were analyzed using standard methods. The use of probiotics provided a 3.2-fold increase in the number of lactobacilli, with a 2.0-fold decrease in enterobacteria and a 6.7-fold decrease in staphylococcus. The digestibility of crude protein increased by 4.7%, crude fat – by 2.8%, and crude fiber – by 2.5%. The digestibility of calcium increased by 2.8%, and phosphorus – by 1.2%. Live weight before slaughter significantly increased by 7.9% (P<0.05), slaughter yield – by 2.5%, pectoral muscle mass – by 9.6%. In the pectoral muscles of the experimental group, the protein content increased by 0.81%, and fat decreased by 0.26%, while the meat quality index decreased from 0.20 to 0.18. The lysine content in muscles increased by 3.2%, tryptophan – by 3.2%, methionine – by 2.7%. The veterinary and sanitary parameters of the experimental chicken meat met regulatory requirements and did not differ from the control. It has been established that Sub-Pro probiotic is an effective and safe means of correcting intestinal microbiocenosis, increasing productivity and improving the quality characteristics of broiler meat.
The comparison of adopter and non-adopter sample reveals three potential adoption inhibitor, security, data privacy, and portability, which underlines the importance of the technical and security perspectives for research investigating the adoption of technology.
Nattakarn Phaphoom, Xiaofeng Wang, S. Samuel et al.· Journal of Systems and Softw...· 111 citations· ⚡8
This study investigates how Lean internal startup facilitates software product innovation in large companies and identifies its enablers and inhibitors, and shows the potential of the method-in-action framework to investigate the Lean startup approach in non-startup context.
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This paper highlights the challenges to conduct proper affect-related studies with psychology, provides a comprehensive literature review in affect theory, and proposes guidelines for conducting psychoempirical software engineering.
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This study conducts a multiple case study on twenty European software startups and proposes a prototype-centric learning model in early stage software startups, and identifies factors that occur as barriers but also facilitators for prototyping in earlystage software startups.
Anh Nguyen-Duc, Xiaofeng Wang, P. Abrahamsson· International Conference on...· 44 citations· ⚡5
It is demonstrated that linker-free PROTACs can outperform traditional designs, marking a paradigm shift in PROTAC development for targeted protein degradation.
Pinal, a 16-billion-parameter foundation model that produces protein candidates from natural-language functional descriptions, supports natural language as a high-level interface for candidate generation in protein design, enabling programmable exploration with reduced reliance on manually specified structural or seque...
A new machine-learning framework aims to improve the success rate of computational protein design while moving away from results that reproduce sequences found in nature.