Jul 2026· Clinical and Translational Oncology· 0 citations· 44 references
Medicine
TL;DR
A comprehensive overview of emerging and targeted therapeutic strategies in colorectal cancer, with emphasis on their molecular basis and clinical relevance, highlights a shift toward precision oncology for improved management of colorectal cancer.
The integration of TME-targeted and individualized therapeutic strategies may offer promising prospects toward achieving durable clinical outcomes in breast cancer treatment.
P. Shankar, Gowthamarajan Kuppusamy, Apsara Unni et al.· Current Cancer Therapy Revie...· 0 citations
This review summarizes the current knowledge on breast cancer, including its epidemiology, anatomy and biology, etiological factors, molecular pathogenesis, diagnostic approaches, and clinically relevant biomarkers, while highlighting recent advances in antibody-drug conjugates, PARP inhibitors, nanotechnology-based dr...
Subham Kumar Singh, Aditya Rai· GLOBAL JOURNAL OF PHARMACEUT...· 0 citations
Key oncogenic signaling pathways, including PI3K/AKT/mTOR and RAS/RAF/MEK/ERK, were discussed in the context of therapeutic targeting and precision medicine and emerging strategies, particularly immunotherapy and combination approaches were addressed.
Xin-Yu Li, Jie Liu, Fang-Fang Huang et al.· Oncology Letters· 0 citations
Recent advances ranging from aberrant genetic and epigenetic alterations; dysregulation of oncogenic signaling pathways; sophisticated crosstalk within the tumor microenvironment; intricate microbiota-inflammation interactions; fundamental discoveries to potential clinical translation; and emerging therapeutic strategi...
Xi-Ya Cheng, Yun-Shu Ma, Jing-Lu Yan et al.· Oncology Research· 0 citations
The future lies in personalised, synergistic regimens across four domains: conventional, targeted, immunological, and emerging approaches, supported by sustained interdisciplinary research and clinical validation.
Vaibhav S. Gite, Rupali N. Nikam, Mukund Pache et al.· Asian Journal of Pharmaceuti...· 0 citations
Overall, siRNA-based strategies may play a crucial role in the future development of precision-oriented therapeutic frameworks in GC research, and this review emphasizes the integration of molecular target selection with delivery system design in a GC-specific context.
Gheysar Seifollahnezhad, B. Erdağ· Experimental oncology· 0 citations
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