Citri reticulatae pericarpium (CP), the dried peel of Citrus reticulata Blanco (Rutaceae), is a common traditional Chinese medicine and edible material with effects of regulating Qi, strengthening the spleen, and resolving phlegm. While its flavonoids have been extensively studied, the polysaccharides, which are the ma...
Haihan Pei, Yupeng Zhang, Kan Ding et al.· Figshare· 0 citations
Poxviruses, African swine fever virus (ASFV), and bacteriophages have independently evolved nucleases that degrade cyclic dinucleotides (CDNs), which are critical second messengers that mediate antiviral responses. This Pearl synthesizes recent advancements in our understanding of viral CDN-degrading nucleases and emph...
Biological discovery and design are increasingly guided by predictive models trained on data from high-throughput technologies rather than costly experiments. However, existing datasets are often biased by overrepresentation of model organisms, causing models to fail in evolutionary studies of non-model species....
Lucas M. Waldburger, Hunter M. Nisonoff, Marissa A. Zintel et al.· Genome Biology· 0 citations
INFORMATION-DYNAMICS MODEL OF PROTEIN-TEMPLATED DNA SYNTHESIS Computational companion for a theoretical study of the bacterial anti-phage reverse transcriptase Drt3b, which synthesizes strictly alternating poly(AC) DNA without any nucleic acid template. BACKGROUND In 2026, Dr. Pujuan Deng et al. (Science) reported that...
Kai Huang, Hongkui Liu, Ziwei Huang· Zenodo (CERN European Organi...· 0 citations
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Abstract Summarizing a collection P of related RNA secondary structures is a key challenge in applications like evolutionary analysis, alternative fold studies and mRNA vaccine design. This requires both clustering the input structures into similar groups and identifying the core structural motifs on which they agree o...
Xinyu Gu, Stefan Ivanovic, Daniel W. Feng et al.· Journal of Computational Bio...· 0 citations
GHKL ATPases share a unique Bergerat ATP-binding fold and regulate diverse biological processes through ATP-dependent conformational changes. An early step of ATP hydrolysis in this family has been attributed to a single highly conserved glutamate residue proposed to function as the general base. However, mutations of...
Kenji Fukui, Ayaka Shibuya, T. Murakawa et al.· eLife· 0 citations
The studies were conducted in 2023-2025 to identify naked oat lines bred at the Nemchinovka Federal Research Centre that combine high productivity, grain quality, and adaptability to the conditions of the Kursk region on typical chernozem. The work was carried out in competitive variety trials (randomized blocks, 6-fol...
E. Logvinova, S. Krivosheev, A. Yemelyanova· Achievements of Science and...· 0 citations
Photorespiration links carbon metabolism with nitrogen assimilation in C3 plants, but its relationship with nitrogen productivity in perennial turfgrass remains unclear. Ten Kentucky bluegrass (Poa pratensis L.) cultivars were screened for photorespiration rate and intensity. ‘Heidi’ and ‘My Holiday’ exhibited the high...
Xiao-Yan Li, Hui-Sen Zhu, Dian Li et al.· Biology· 0 citations
Aluminum chloride (AlCl₃) is a ubiquitous environmental toxicant that induces multi-organ toxicity, primarily via oxidative stress and inflammatory mechanism cascades. Panax ginseng, renowned for its pharmacologically active ginsenosides, exhibited potent antioxidant and anti-inflammatory activities. Accordingly, this...
Fatimah A. Alsaeed, Sayed Soliman Abdel Ghfar, Montaser Elsayed Ali· Frontiers in Veterinary Scie...· 0 citations
Multiomics and structural in silico analyses of publicly available experimental genomic, transcriptomic, and proteomic datasets are performed, combined with structural modeling, to investigate the glycosylation pathway of the medically important snake B. jararaca, suggesting that the glycosylation machinery is coupled...
Thales A. M. Fernandes, M. Nishiyama-Jr· International Journal of Mol...· 0 citations
Background/Objectives: No shoulder-specific percentile reference range exists for postoperative C-reactive protein (CRP) or erythrocyte sedimentation rate (ESR) after reverse shoulder arthroplasty (RSA); clinicians rely on time-invariant thresholds borrowed from lower-extremity cohorts, and the ESR trajectory is unchar...
Jaemin Lee, S. Yang, Doo-Sup Kim· Diagnostics· 0 citations
Infant-associated bifidobacteria utilize lacto-N-biose I (LNB) and galacto-N-biose (GNB), major components of human milk oligosaccharides and intestinal mucin, respectively, through the GNB/LNB metabolic pathway. A UDP-glucose–hexose-1-phosphate uridylyltransferase (GalT) from Bifidobacterium longum JCM 1217 (BlGalT2)...
M. Sato, C. Yamada, M. Nishimoto et al.· bioRxiv· 0 citations
A new machine-learning framework aims to improve the success rate of computational protein design while moving away from results that reproduce sequences found in nature.
