AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
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2,141 papers
SIRT1–GAPDH signaling represents a post-translational axis linking sirtuin activity directly to glycolytic enzyme function, distinct from SIRT1's traditional transcriptional roles and serving as a viable molecular checkpoint in microglial immunometabolism.
The results suggest that roles of CetZ1 in cell shape or potentially the organisation and structure of the cell poles influence the polar assembly of the motility machinery.
Structural and biochemical studies have elucidated the architecture of the nsp14 N7-methyltransferase domain, revealing an S-adenosyl-L-methionine (SAM)-dependent fold with a defined cofactor-binding site and an adjacent cap-binding pocket that orients the RNA substrate for methyl transfer.
The temporal decline of circulating miR-1-3p levels and the identification of PKC support a model in which miR-1-3p may contribute to functional maturation of the ZR through modulation of non-canonical intracellular signaling pathways.
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The data demonstrate that MRO is poised to play a role in the coordination of periovulatory events through the EGF and progesterone signaling pathways through the EGF and progesterone pathways.
A cheap density prior is introduced over natural protein activations and keeps only the candidates that remain typical under it, a training-free post-hoc step the authors call Mahalanobis filtering that improves both the property score and the structural plausibility of the sequences it keeps at negligible cost, withou...
3D models of the C-terminal SC region suggest that the major C-terminal domain of SC folds into a single-layer β-sheet structurally similar to the membrane occupation and recognition nexus (MORN) family of tandem repeats, which is critical for understanding SC-mediated fibrin generation.
Findings suggest that low-dose ethephon elicitation may be a simple strategy to enhance phycobiliprotein accumulation in Arthrospira platensis.
This study investigated the synergistic effects of supercritical carbon dioxide (SCCD) combined with sucrose treatment on the foaming properties and freeze-thaw stability of egg white protein (EWP). The results demonstrated that SCCD-sucrose treatment significantly enhanced the foaming capacity, achieving a maximum...
A divergent regulation of CD29 and CD49b integrins associated with HLA-B27 status in Iraqi AS patients is suggested and longitudinal validation is required to confirm their clinical utility as diagnostic or therapeutic targets.
This is the first study reporting the use of phage/bacterium system and aggregation induced emission luminogen for detection of antibiotic residues in food sample.
This study provides the first comparative transcriptomic, structural, and functional characterization of AMPs and anti-microbial proteins in N. quadripunctatus and N. littoralis, offering important foundational insights for the future development of bacteria-specific AMPs as alternatives to conventional antibiotics.
Proof of concept for watermarking AI-generated proteins while preserving biological function.
A new machine-learning framework aims to improve the success rate of computational protein design while moving away from results that reproduce sequences found in nature.
Scientists are using AlphaFold to strengthen a photosynthesis enzyme for resilient, heat-tolerant crops.
Explore how AlphaFold has accelerated science and fueled a global wave of biological discovery.
AlphaFold has revealed the structure of a key protein behind heart disease
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