This is the first study that provides direct in vitro evidence of Don induced cell cycle arrest at G2/M phase through highly upregulated p21, with no increase in p53 protein levels, suggesting p53-independent p21 induction.
Inji Shikhaliyeva, G. Albayrak, Cenk Kığ et al.· Toxicology· 0 citations
Due to its importance and wide adoption, wheat cultivation is promptly required to shift towards sustainable practices, reducing the dependency on chemical components. Among bio-based solutions aimed at securing the sustainability of wheat cultivation, biostimulants offer a versatile platform of eco-friendly tools assu...
Amer Chabili, Z. Hakkoum, F. Minaoui et al.· Plant Science· 1 citation
Control electrical stimulation significantly enhanced mucus secretion under optimized parameters of 10 V and 15 cycles, resulting in a 3.59-fold increase in mucus-associated protein output and clear electrophoretic protein profiles.
Xing Lu, Yong Long, Xiaozhen He et al.· Comparative Biochemistry and...· 0 citations
Evaluating the effectiveness of embeddings from five Protein Language Models, including ProtBERT-BFD, ESM-2, ProtALBERT, ProLLaMA, and ProtGPT-2, as input features for various machine learning classifiers suggests that while current embeddings offer strong performance, further advancements in feature extraction and mod...
Karthik Avinash, S. Tejas, Sriram Mamidala et al.· Analytical Biochemistry· 0 citations
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This study constructed a pH-responsive P-TN/SF@Fe-Cur composite coating that demonstrated significant anti-infective, anti-inflammatory, antioxidant, pro-angiogenic, and pro-osteogenic effects in rat subcutaneous infection and femoral defect models.
A new machine-learning framework aims to improve the success rate of computational protein design while moving away from results that reproduce sequences found in nature.
