AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
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2,039 papers
Findings establish PtoeIF5A1 in poplar as a pleiotropic regulator integrating developmental cues, programmed cell death, and stress responses; and as a valuable genetic resource for breeding stress-resilient woody plants.
Abstract Probiotic efficacy depends not only on gastrointestinal survival but on mucosal adhesion and the capacity to deliver bioactive molecules at the intestinal surface. This study optimized a whey protein isolate (WPI)–chitosan (CS) matrix for spray drying microencapsulation of Lacticaseibacillus casei BL23 using c...
AIM Colorectal cancer (CRC) is a widespread health issue that attains high mortality. The adaptor protein SH3BP2 amplification results in metabolic changes, oxidative stress, NK cell activity, and inflammation. The NK cells are capable of destroying tumor cells without prior activation, help prevent metastasis, and hav...
Protein language models (pLMs) learn sequence patterns at evolutionary scale, but these patterns remain inaccessible within these “black box” models. To discover them, we developed MotifAE, an unsupervised framework based on the sparse autoencoder (SAE) architecture that projects pLM embeddings into an interpretable, s...
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This is an updated version of a presentation at Edinburgh University in June with some editing and additional slides on BindingDB patent curation Presented at the Scaggs School of Pharmacy, University of California San Diego, August 28th 2026 as guest of Prof. Michael Gilson Abstract The beta amyloid (APP) cleaving enz...
Many insects manipulate plants by injecting effector proteins. In one extreme example of this molecular "hijacking," Hormaphis cornu aphids inject bicycle proteins into Hamamelis virginiana, contributing to the development of novel organs called galls. Bicycle proteins share no amino acid sequence similarity with prote...
Overview A prospectively frozen benchmark suite for leakage-safe multi-omic integration. It tests predictive performance, modality utility, model-capacity effects, missingness handling, null behavior, exploratory external transport, and failure handling without making claims of clinical utility or causal biological inf...
Overview A prospectively frozen benchmark suite for leakage-safe multi-omic integration. It tests predictive performance, modality utility, model-capacity effects, missingness handling, null behavior, exploratory external transport, and failure handling without making claims of clinical utility or causal biological inf...
Recent progress is reviewed in applying AI for neuroscience along this scale axis: structure prediction for proteins, simulation-based inference for biophysical neurons, latent and dynamical models for neural populations, task-trained networks as minimal models of circuit computation, computer vision for animal behavio...
Coastal waters off Nouakchott support fisheries and, more recently, offshore oil activity and iron-ore export, all of which raise the risk of marine contamination. Local biomonitoring tools are still lacking. We asked whether the wedge clam Donax rugosus , abundant on Nouakchott’s beaches, can serve as a sentinel. Acet...
Hyper-Fold is introduced, a rank-K separable convolutional backbone approaching this ceiling at message-passing cost, suggesting that a sufficiently expressive 3D backbone recovers information that fusion architectures previously borrowed from evolution-scale pretraining.
Proof of concept for watermarking AI-generated proteins while preserving biological function.
A new machine-learning framework aims to improve the success rate of computational protein design while moving away from results that reproduce sequences found in nature.
Scientists are using AlphaFold to strengthen a photosynthesis enzyme for resilient, heat-tolerant crops.
Explore how AlphaFold has accelerated science and fueled a global wave of biological discovery.
AlphaFold has revealed the structure of a key protein behind heart disease
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