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14,750 papers

#machine learning Preprint Open access Oct 2026

Retrieval-Augmented Generation for Predicting Cellular Responses to Gene Perturbation

Predicting transcriptional responses to genetic perturbations is fundamental to functional genomics and therapeutic discovery. Recent deep learning models have shown promise in single-cell perturbation response prediction, but they typically generate each response in isolation, without explicitly leveraging related per...

Andrea Giuseppe Di Francesco, Andrea Rubbi, Rishabh Jain et al. · 0 citations
#machine learning Preprint Open access Oct 2026

3BASiL: An Algorithmic Framework for Sparse plus Low-Rank Compression of LLMs

Sparse plus Low-Rank $(\mathbf{S} + \mathbf{LR})$ decomposition of Large Language Models (LLMs) has emerged as a promising direction in model compression, aiming to decompose pre-trained model weights into a sum of sparse and low-rank matrices $(\mathbf{W} \approx \mathbf{S} + \mathbf{LR})$. Despite recent progress, ex...

Mehdi Makni, Xiang Meng, Rahul Mazumder · 0 citations
#machine learning Preprint Open access Oct 2026

PaReGTA: A Temporally Aware LLM-Based Patient Representation Framework for EHR Analytics

Temporal information in structured electronic health records (EHRs) is often lost in sparse one-hot or count-based representations, while sequence models can be costly and data-hungry. We propose PaReGTA, an LLM-based encoding framework that (i) converts longitudinal EHR events into visit-level templated text with expl...

Kihyuk Yoon, Lingchao Mao, Catherine Chong et al. · 0 citations
#machine learning Preprint Open access Oct 2026

Uncertainty Quantification in Federated Granger Causality Learning

Granger causality identifies predictive dependencies in multivariate time series. In distributed settings where parties cannot share data, federated causal learning enables joint analysis. Most federated causal methods assume that clients observe the same features and infer causal relationships as point estimates, with...

Ayush Mohanty, Nazal Mohamed, Nagi Gebraeel · 0 citations
#machine learning Preprint Open access Oct 2026

Synthetic Time Series Generation via Complex Networks

Time series data are essential for a wide range of applications, yet access to high-quality datasets is often constrained by privacy concerns, acquisition costs, and labelling challenges. Synthetic time series generation has emerged as a promising approach to address these limitations. In this work, we investigate the...

Jaime Vale, Vanessa Freitas Silva, Maria Eduarda Silva et al. · 0 citations
#machine learning Preprint Open access Oct 2026

Mechanistic Evidence for Spectral Structures in Prior-Data Fitted Networks

Prior-Data Fitted Networks (PFNs) perform approximate Bayesian inference in a single forward pass, and tabular foundation models (TFMs) built on them are now widely used. To understand what networks infer internally, recent mechanistic studies of TFMs locate where predictions form, but treat these models as tabular pre...

Kaustubh Sharma, Srijan Tiwari, Ojasva Nema et al. · 0 citations
#machine learning Preprint Open access Oct 2026

Local Timescale Gates for Timescale-Robust Continual Spiking Neural Networks

Spiking neural networks (SNNs) promise energy-efficient artificial intelligence on neuromorphic hardware but struggle with tasks requiring both fast adaptation and long-term memory, especially in continual learning. We propose Local Timescale Gating (LT-Gate), a neuron model that combines dual time-constant dynamics wi...

Devansh Deep, Ansh Tiwari, Ayush Chauhan · 0 citations
#machine learning Preprint Open access Oct 2026

Fractional Heat Kernel for Semi-Supervised Graph Learning with Small Training Sample Size

We develop a source-driven fractional heat-kernel framework for semi-super\-vised graph learning that combines nonlocal propagation with sustained label information. A fixed nonzero label source compatible with the Laplacian null space prevents asymptotic collapse into that space, providing a mechanism for mitigating o...

Farid Bozorgnia, Vyacheslav Kungurtsev, Shirali Kadyrov et al. · 0 citations
#machine learning Preprint Open access Oct 2026

AdaSwitch: An Adaptive Switching Meta-Algorithm for Learning-Augmented Bounded-Influence Problems

We study history-dependent online problems with a possibly inaccurate prediction of the future request sequence. Motivated by several real-world applications, we introduce a \emph{bounded-influence} framework in which past decisions and requests affect the future optimal value by only a bounded amount. Within this fram...

Xi Chen, Yuze Chen, Shibo Dai et al. · 0 citations
#machine learning Preprint Open access Oct 2026

The Sample Complexity of Membership Inference and Privacy Auditing

A membership-inference attack gets the output of a learning algorithm, and a target individual, and tries to determine whether this individual is a member of the training data or an independent sample from the same distribution. A successful membership-inference attack typically requires the attacker to have some knowl...

Mahdi Haghifam, Adam Smith, Jonathan Ullman · 0 citations
#machine learning Preprint Open access Oct 2026

BrainATCL: Adaptive Temporal Brain Connectivity Learning for Functional Link Prediction and Age Estimation

Functional Magnetic Resonance Imaging (fMRI) is an imaging technique widely used to study human brain activity. fMRI signals in areas across the brain transiently synchronise and desynchronise their activity in a highly structured manner, even when an individual is at rest. These functional connectivity dynamics may be...

Yiran Huang, Amirhossein Nouranizadeh, Christine Ahrends et al. · 0 citations
#machine learning Preprint Open access Oct 2026

Brain foundation model-guided source-selective domain adaptation for cross-subject EEG decoding

Cross-subject motor-imagery electroencephalography (MI-EEG) decoding remains challenging because substantial inter-subject variability can cause both negative transfer from poorly matched source subjects and persistent distribution discrepancies between source and target domains. Existing multi-source domain adaptation...

Jinzhou Wu, Baoping Tang, Qikang Li et al. · 0 citations

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Microsoft Research Blog Oct 12, 2026

Simulating student learning for better AI tutoring

StudentSim is a research system for evaluating and improving AI tutoring tools before they are tested with learners. It models how individuals may engage with tutors, giving feedback to improve tutor performance across subjects like chess, writing, and mathematics. The post Simulating student learning for better AI tutoring appeared first on Microsoft Research.

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