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1,411 papers
This review dissects the technological foundations and limiting factors of multiplex genome editing, focusing on guide RNA (gRNA) array engineering, delivery constraints, and scale‐dependent safety risks.
Informing Biosafety Policies and Regulations: Gene Editing Technologies and Their Applications in Philippine Livestock and Fisheries synthesizes the science, potential applications, and biosafety implications of genome editing in animals. This inaugural NCBP | DOST BC Secretariat Technical Publication examines opportun...
The revelation of the previously unreported tragic death of a 6-year-old girl in Shanghai who received an experimental gene-edited intervention stands in stark contrast to the excitement surrounding the successful use of another experimental gene-edited intervention in an infant boy in Philadelphia just about a year ea...
Alphaviruses are positive-sense single-stranded RNA viruses belonging to the family Togaviridae; they are also part of the non-taxonomic group of arboviruses and constitute a group of arboviruses of major which are of great clinical and epidemiological relevance worldwide. These viruses can be broadly classified into e...
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Informing Biosafety Policies and Regulations: Gene Editing Technologies and Their Applications in Philippine Livestock and Fisheries synthesizes the science, potential applications, and biosafety implications of genome editing in animals. This inaugural NCBP | DOST BC Secretariat Technical Publication examines opportun...
Erythritol, as an important zero-calorie sweetener, is widely used in food, pharmaceutical, and daily chemical industries. However, its industrial production has long faced two major challenges: high raw material costs and severe foaming during fermentation, which significantly complicate process control and increase o...
This review synthesizes current advances in CRISPR-based DNA methylation editing for cancer epigenomics, critically evaluates key challenges, including off-target activity, context-dependent outcomes, delivery and durability, and outlines future directions integrating locus-specific editing with multi-omics profiling,...
Protein metabolism is fundamental to human physiology, integrating dietary protein digestion and absorption, amino acid catabolism, nitrogen disposal, biosynthesis, regulatory signalling, and systemic adaptation. This review synthesizes foundational biochemical knowledge and recent advances to clarify the organization,...
Stem cells are found in many organs, where they play essential roles in tissue repair and normal renewal. They have two defining properties: the ability to self-renew and the ability to differentiate into specialized cell types. This process is tightly regulated. Disruptions in stem-cell proliferation or differentiatio...
Across 13 prediction tasks spanning post-transcriptional regulation, RNA fate and expression output, EukaUTR models matched or exceeded the strongest external baselines on nearly all tasks, with relative improvements of up to 27.45%.
Retinitis pigmentosa (RP) affects 1 in 3,000 individuals worldwide, with 30%-40% of cases inherited as autosomal dominant (AD). Mutations in RHO (RP4) are the most common cause of ADRP. Because most RHO mutations exert gain-of-function or dominant-negative effects, conventional gene supplementation is insufficient, req...
The available evidence underscores both the therapeutic potential and inherent complexity of nanocarrier-mediated gene and nucleic acid therapies for RA, emphasizing the necessity for optimized delivery strategies, rigorous safety assessments, and biomarker-guided patient stratification to achieve successful clinical t...
GPT-Lab
· gpt-lab.eu
Oct 8, 2026
Exploring how generative AI could make machine vision more accessible to businesses. The post GenEye in a Box: Making Machine Vision Something You Can Just Ask For appeared first on GPT-Lab.
A Blog post by Ai2 on Hugging Face
A Blog post by ServiceNow-AI on Hugging Face
“InstructMesh” can generate designs for everyday objects that are easy to edit and fabricate for both experts and newcomers to 3D modeling.
Proof of concept for watermarking AI-generated proteins while preserving biological function.
Algorithms & Theory
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