gene editing

Assessment of omics and genome editing approaches for addressing climate challenges: Enhancing stress tolerance in tea (Camellia sinensis (L.) O. Kuntze)

The role of omics and genome editing is underscores the role of omics and genome editing in advancing research to improve tea cultivation and support its resilience against 21st Century climate changes.

Harnessing plant susceptibility genes into strategies for enhanced disease resistance

Key translational challenges, including pleiotropy, genetic background effects, pathogen adaptation, transgene footprints and regulatory divergence, that must be addressed to harness S genes for durable and agronomically balanced crop resistance are highlighted.

EFFECTIVENESS OF TREATING GENETIC DISEASES BY GENE THERAPY

This article analyzes the effectiveness of gene therapy in treating genetic diseases, its main molecular mechanisms, and modern technologies. Key therapeutic approaches such as gene addition, gene function restoration, gene expression silencing, and targeted genome editing are covered. The potential of modern gene deli...

CRISPR/Cas9-Mediated Knockout of LXRα and LXRß in MCF-7 Breast Cancer Cells, Revealing Their Roles in Target Gene Regulation and Cell Proliferation

CRISPR/Cas9‐mediated gene editing and its application for developing novel genotypes in medicinal plants

Developing rice tolerance to abiotic stress through gene editing technologies

Optimized cuvette-based electroporation of buffalo and caprine zygotes supports the delivery of up to 21 kilobase plasmids

The advent of precise genome editing technologies has revolutionized the capacity to manipulate animal genotypes and phenotypes, offering a targeted complement to conventional selective breeding approaches. Efficient delivery of exogenous DNA into livestock embryos remains a major technical bottleneck, particularly...

From conventional breeding to gene editing: advances in biotechnological strategies for improving abiotic stress tolerance in rice

Climate-resilient rice crop improvement using CRISPR–Cas technology

A RUBY-Based Visual Hairy Root Transformation and CRISPR-PTG Genome-Editing System in Eucommia ulmoides

Eucommia ulmoides Oliv. is a woody plant with significant medicinal and industrial value. However, the lack of an efficient genetic transformation and gene-editing system has seriously hindered the research on its functional genes and the progress of molecular breeding. To break through this technical bottleneck, this...

Next-generation biotechnology for improving abiotic stress tolerance in rice

CRISPR/Cas9-Mediated Editing of Terpene Synthase Gene Reduces Volatile Emission and Attraction of Hypothenemus hampei to Coffea arabica Fruits

The coffee berry borer (CBB), Hypothenemus hampei (Ferrari) (Coleoptera: Curculionidae: Scolytinae), is one of the most destructive pests of coffee, causing significant losses in yield, bean quality, and overall crop profitability. Current integrated pest management strategies reduce damage but cannot prevent insects f...