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Dosing decisions for narrow-therapeutic-index and highly variable drugs have historically relied on population-based nomograms, therapeutic drug monitoring, and clinician heuristics, which frequently under- or over-dose individual patients. Machine learning (ML) offers a data-driven alternative capable of integrating g...
Advanced drug delivery systems (DDS) — including polymeric and lipid nanoparticles, lipid nanoparticles (LNPs) for nucleic acid therapeutics, solid oral dosage forms, and three-dimensional (3D)-printed and stimuli-responsive platforms — require the simultaneous optimization of dozens of interacting formulation and proc...
Advanced drug delivery systems (DDS) — including polymeric and lipid nanoparticles, lipid nanoparticles (LNPs) for nucleic acid therapeutics, solid oral dosage forms, and three-dimensional (3D)-printed and stimuli-responsive platforms — require the simultaneous optimization of dozens of interacting formulation and proc...
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