Harmonized Residue-Level Dataset of Human Co-Translational Protein Folding Kinetics and Downstream mRNA Secondary Structure (1,270 Non-Redundant Proteins)
Sep 2026· Zenodo (CERN European Organization for Nuclear Research)
Abstract
Overview This dataset contains residue-level biophysical measurements, translational kinetics profiles, and downstream mRNA thermodynamic stability metrics across 1,270 non-redundant human proteins (410,151 total residue observations). The dataset is designed to benchmark whether co-translational protein folding is paced by local codon supply (tAI, CAI) or downstream mRNA secondary structure (minimum free energy, MFE). Column Name Type Description UniProt_ID String Canonical UniProtKB accession identifier (e.g., P04637) PDB_ID String Experimental RCSB PDB structure identifier (resolution
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