The prevalence and significance of bronchial hyperresponsiveness (BHR) in patients with non‐cystic fibrosis (CF) bronchiectasis remain unclear. The objective is to determine the prevalence of BHR, defined as a post‐bronchodilator forced expiratory volume in 1 s (FEV1) improvement > 10%, in children with non‐CF bronchiectasis and to assess its association with clinical, functional, and radiological characteristics.
Background: Non-cystic fibrosis bronchiectasis (NCFB) is a chronic lung condition that causes ongoing inflammation of the airways of the lungs, multiple lung infections and progressive airway structural damage, resulting in repeated exacerbations and poor quality of life. Recurrent exacerbation should be treated with l...
S. Hiremath, Harsha Hanji, Vinayakumar Jogondra et al.· International Journal of Dru...· 0 citations
Bronchiectasis is a widely recognised chronic respiratory illness classified in severity by frequency of exacerbations within the past year, percent predicted forced expiratory volume in 1 second (%FEV1), previous hospital admissions and radiological severity, among other factors. The physiological process is understoo...
Primary Ciliary Dyskinesia (PCD) is a genetic disorder characterized by respiratory infections leading to chronic airway colonization and progressive lung damage. The aim of this study is to evaluate prevalence and longitudinal changes of respiratory microbiological profile in children and young adults with PCD, and th...
V. Ferraro, Valentina Tonazzo, A. Pandolfo et al.· Pediatric Pulmonology· 0 citations
Long considered as a rare and neglected disease, non-cystic fibrosis bronchiectasis in children is now recognized as an emerging cause of chronic respiratory morbidity worldwide. Its incidence is strikingly variable, ranging from 0.2-2.3 per 100,000 children annually in high-income countries to more than 700 per 100,00...
I. Mansouri, D. Benchaji, A. Errami et al.· Revue des maladies respirato...· 0 citations
Pulmonary alveolar proteinosis (PAP) is a rare disorder characterized by abnormal accumulation of surfactant within the alveoli, leading to impaired gas exchange and progressive respiratory symptoms. We report a 40-year-old stone grinder presenting with chronic cough, dyspnea, weight loss and hypoxemia. High-resolution...
Idiopathic subglottic stenosis (iSGS) is a rare fibrotic condition causing fixed extrathoracic airway obstruction, predominantly affecting postmenopausal women. The expiratory disproportion index (EDI), calculated as forced expiratory volume in one second (FEV1) (mL)/peak expiratory flow (PEF) (L/min), can help differe...
S. Sridhara, Anirudh Burli· Proceedings· 0 citations
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