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Insights into the microcirculation in pediatric chronic spontaneous urticaria: A nailfold videocapillaroscopy study

Oct 2026 · Pediatric Allergy and Immunology · Vol 37 · 0 citations · 31 references
Medicine

TL;DR

Nailfold microvascular alterations in children with CSU are investigated and their associations with disease activity, disease control, autoreactivity, and inflammatory markers are investigated.

Abstract

Chronic spontaneous urticaria (CSU) is increasingly recognized as a systemic inflammatory disease with endothelial involvement extending beyond the skin. Nailfold videocapillaroscopy (NVC) has demonstrated systemic microvascular abnormalities in adults with CSU, but pediatric data are lacking. We investigated nailfold microvascular alterations in children with CSU and their associations with disease activity, disease control, autoreactivity, and inflammatory markers.

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