TL;DR
A cascade-driven dual-signal attenuation strategy that holds great promise for high‑performance electrochemical biosensing in complex biological samples.
In sensing analysis, controlling signal switch through targets is a key method to ensure detection sensitivity. To improve the control effect, an antifouling sensor based on controlled-release and co-reaction catalytic strategies was designed. Concretely, the gel interface with the biocompatible red cell membrane as th...
Electrocatalytically amplified electrochemical immunosensing is a powerful strategy for sensitive and interference-free detection of biomarkers. Herein, we report a high-performance electrochemical immunosensor enabled by a hierarchical hybrid architecture comprising Ru nanodots anchored on titanium oxynitride nanoflak...
A novel, enzyme-free surface-enhanced Raman scattering (SERS) platform based on a "dual-hotspot amplification" strategy that enhances detection sensitivity but also provides a useful design concept for the ultrasensitive analysis of carbohydrate-derived biomarkers.
This work presents a novel strategy for the highly sensitive detection of Gal-3, leveraging the synergistic dual-quenching mechanism to achieve excellent analytical performance, thereby holding significant promise for clinical diagnostics and early disease monitoring applications.
A sensitive and label-free electrochemical immunosensor based on a g-C₃N₄/MgO nanocomposite-modified electrode for the selective detection of CYFRA21-1 has great promise for clinical diagnosis and point-of-care detection of lung cancer biomarkers because of its affordability, simplicity, and sensitivity.
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