Aug 2026· Proceedings of the National Academy of Sciences of the United States of America· Vol 123 34, pp.
e2610136123
· 0 citations· 50 references
Medicine
TL;DR
This study provides chemical and genetic insights into the evolution of tomato flavor during domestication and subsequent improvement, identifying the complexity of genetic control of fruit flavor chemicals as well as a number of new alleles that can be used to improve the contents of flavor-linked chemicals.
Abstract
Extensive selection for yield and disease resistance during tomato crop improvement has led to flavor loss in modern commercial tomatoes in comparison with heirloom varieties. To investigate the chemical and genetic architecture of tomato flavor through both domestication and improvement, we analyzed flavor-related chemicals across 558 globally collected accessions comprising wild relatives, semidomesticated and domesticated populations, including uncharacterized Latin American accessions. Key flavor volatiles exhibit major differences across accessions. A genome-wide association study was used to detect associations between genetic loci and flavor-related chemical contents, including sugars, acids, and volatiles. Multiple genetic loci linked to known genes encoding flavor metabolism enzymes, as well as many new loci, were identified. Among the newly identified loci, a gene encoding a previously uncharacterized lipase (Sl-LIP100) was experimentally proven to have an important role in synthesis of lipid-derived flavor volatiles. This enzyme is responsible for synthesis of several important five- and six-carbon flavor volatiles. In sum, this study provides chemical and genetic insights into the evolution of tomato flavor during domestication and subsequent improvement, identifying the complexity of genetic control of fruit flavor chemicals as well as a number of new alleles that can be used to improve the contents of flavor-linked chemicals.
Tomato (Solanum lycopersicum L.) is an important vegetable crop valued for its nutritional quality, wide adaptability and economic significance. The present study was conducted to evaluate genetic variability, character association and genetic diversity among tomato accessions for yield and its contributing traits. The experiment was carried out during the spring-summer season of 2020 and 2021 at the experimental field of horticulture, School of Agriculture, Lovely Professional University. A total of 26 tomato accessions, comprising 6 repatriated genotypes and 20 hybrids developed through a full diallel mating design, were evaluated in a randomised complete block design (RCBD) with 3 replications and 15 quantitative and quality-related characters. Significant variation was found among the different germplasms for all characters. Yield and yield contributing characters showed high heritability along with genetic gain, indicating major role of these characters in expression of these characters. Yield per plant exhibited a strong and positive relationship with number of fruits per plant, fruit width, fruit length and mean fruit weight. Path coefficient analysis indicated that the number of fruits per plant and reducing sugar content exerted the highest positive direct influence on yield. Principal component analysis explained 81.70 % of the total variation through five components. Cluster analysis grouped accessions into two major clusters irrespective of geographic origin, indicating wide genetic diversity. Accessions T10 and F1022 were identified as the most divergent and may serve as promising parents for yield improvement in tomato breeding programs.
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