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Large language models for digital mental health: an HCI-centered scoping review

Oct 2026 · npj Digital Medicine
Digital Mental Health Interventions

Abstract

Large language models (LLMs) are rapidly reshaping digital mental health, yet how these systems are designed, used, and evaluated remains poorly characterized. We conducted an HCI-centered scoping review of 84 studies examining mental health tasks, stakeholders, interaction paradigms, foundation models, evaluation methods, and outcome measurement. Counseling and support and self-help and well-being accounted for 73.8% of studies, while clinician support and crisis and risk support remained uncommon. Mixed-methods user studies predominated (42.9%), with only three randomized controlled trials and eight studies classified as longitudinal or field evaluations. Technical and response performance was assessed in 81.0% of studies, compared with 29.8% assessing mental health symptoms and clinical outcomes and 7.1% including longitudinal follow-up. Outcome profiles differed across intended tasks. Building on these findings and established evaluation guidance, we propose a task-oriented framework aligning evaluation domains, measurement approaches, and assessment timing with intended use.

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