Axial Excitation-Energy Transport and Inter-Tube Hopping in Microtubules: A Falsifiable Experimental Framework for Molecular Transport, Crosstalk, ELF Modulation, and Array Feasibility

Abstract

Polymerized microtubules contain ordered aromatic residues capable of supporting electronic excitation migration, but the directionality, range, and engineering usefulness of that transport remain unknown. This manuscript presents a falsifiable experimental framework for testing preferential axial excitation-energy transport in intact microtubules, transfer between neighboring microtubules, channel crosstalk, and the feasibility of a nanoscale transduction array.The framework distinguishes the previously reported two-dimensional photoexcitation diffusion length from the unmeasured one-dimensional axial quantities required for an engineered device. It defines molecular-scale experiments that explicitly separate direct donor-acceptor transfer from a microtubule-mediated component, with independent replication and model comparison. An engineering-positive result additionally requires the lower 95% confidence bound on axial attenuation length to reach at least 20 nm.Subsequent stages test inter-tube hopping and channel identity, preservation of transport properties following fabrication, and electrical, mechanical, and magnetic modulation as orthogonal hypotheses. The confirmatory electrical panel is prespecified at 7.8, 14.3, 20.8, 27.3, 33.8, and 39.0 Hz with matched off-panel, DC, sham, electrochemical, and field-delivery controls. The program defines explicit F1-F7 falsification and stop rules. The framework stands independently of any claim about consciousness.