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Identification of altered biological processes in heterogeneous RNA-sequencing data by discretization of expression profiles

Andrea Lauria S. Peirone M. Del Giudice Francesca Priante P. Rajan M. Caselle S. Oliviero Matteo Cereda
· 1 citation · 94 references

TL;DR

GSECA showed that, in prostate cancer, PTEN loss appears to establish an immunosuppressive tumor microenvironment through the activation of STAT3, and low PTEN expression levels have a detrimental impact on patient disease-free survival.

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