Identification of altered biological processes in heterogeneous RNA-sequencing data by discretization of expression profiles
GSECA showed that, in prostate cancer, PTEN loss appears to establish an immunosuppressive tumor microenvironment through the activation of STAT3, and low PTEN expression levels have a detrimental impact on patient disease-free survival.
Andrea Lauria, S. Peirone, M. Del Giudice et al.
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