Supplementary Figure 1 from FGFR1 Suppresses STING-Mediated Interferon Response in Endocrine Therapy–Resistant Breast Cancer

Abstract

A) Western blot shows FGFR1 protein levels in P-T47D and TR-T47D cells. GAPDH as loading control. (B–C) Relative expression of FGFR1 and STING1 respectively, in P-T47D and TR-T47D cells, measured by RT-qPCR and normalized to ACTB and RPLP1. Fold change was calculated relative to the geometric mean of ΔCq of the P-T47D condition. Boxplots show the median and IQR with whiskers extending to the most extreme data point within 1.5 × IQR of the box edges; individual points represent biological replicates. D) Mean cGAS immunofluorescence intensity in P-T47D and TR-T47D cells in nuclear (left; each point = one nucleus) and non-nuclear (right; each point = one image) compartments.