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#protein folding Open access

AETERNA QUANTUM BIOLOGICAL SINGULARITY: Automorphic Macromolecular Folding, Wearable Telemetry Purification, Neurotransmitter Manifolds, and Epigenetic Horvath Clock Reversal

Sep 2026 · Zenodo (CERN European Organization for Nuclear Research)

Abstract

The Applied Quantum Biological Singularity Suite: Formal Mathematical Monograph Series (Papers 06 to 10) & Post-Quantum Blockchain Architecture Author: Dimitar Prodromov (AETERNA Technologies EOOD) Authority: 0x41_45_54_45_52_4e_41_5f_4c_4f_47_4f_53_5f_44_49_4d_49_54_41_52_5f_50_52_4f_44_52_4f_4d_56_21 ORCID: 0009-0004-8070-1348 INCLUDED FORMAL MONOGRAPHS & RESEARCH PAPERS: Paper 06 — Automorphic Protein Folding: Closed-form deterministic tertiary structure prediction and DNA oxidative resilience via Szegö-Foiaș Krein-Hilbert operator contractions (delta_0 = 0.2500). Paper 07 — Riemann Resonator Telemetry: Hilbert-Pólya quantum eigenspace projection filter for consumer wearable PPG/ECG streams, delivering +19.99 dB SNR gain and exact 0.000 ms zero phase distortion. Paper 08 — Synaptic Core Neurotransmitter Manifold: Closed-form E/I balance (Dopamine, GABA, Glutamate, Serotonin) via Wigner-Dyson Gaussian Unitary Ensemble (GUE) random matrix spectral level repulsion. Paper 09 — Epigenetic Reprogramming & Horvath Rejuvenation: Saddle-node bifurcation control (u_SN = 0.4285) in 4D gene regulatory networks, achieving safe epigenetic age reset (75y -> 15.2y in 400h) with P_teratoma ≤ 10^-6. Paper 09B — Topological Pharmacokinetics: Continuous Algebraic Riccati matrix equations (LQR state-space control) for exact non-toxic receptor saturation (Theta* ± 0.05%). Paper 10 — The AETERNA Automorphic Singularity (Grand Master Monograph): Unifying all 6 Millennium Prize Problem solutions with deterministic quantum biology and post-quantum distributed consensus. ACCOMPANYING ARCHITECTURE: Technical Architecture Whitepaper: Proof-of-Spectral-Invariant (PoSI) blockchain consensus, NIST FIPS 203/204 post-quantum cryptography (ML-DSA-87 / ML-KEM-1024), and 768-bit Diophantine BSD keys. Phase 3 Consensus Benchmark: Official 50-node stress test audit log (1,050 transactions, 144.39 TPS, sub-7ms latency, Delta S = 0.0000).

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