Open access
Unique transcriptomic alterations in 5XFAD;PS19 mouse model identify glial lipid dysregulation and coordinated microglial–oligodendrocyte responses
Jung Hyun Park
Byungwook Kim
Mamun Md Al‐Amin
M. Tate
A. D. Sharify
Sutha K. John
Hande Karahan
Hui-Chen Lu
L. Dabin
Jungsu Kim
Medicine
Abstract
Alzheimer's disease (AD) features amyloid beta (Aβ) plaques and tau tangles, yet how their coexistence reshapes brain transcriptomic programs remains unclear.