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Subphenotypes of Sickle Cell Disease: A Guide to Targeting Treatment?
Aug 2026 · American journal of hematology/oncology · Vol 101, pp. 2505 - 2508 · 0 citations
· 17 references
Medicine
Abstract
The pathophysiology of sickle cell disease, a phenotype caused by several common and many rarer genotypes, flows “down-stream” from the initiating event of sickle hemoglobin (HbS) polymerization [1]. Twenty years ago, building on prior observations