Brain morphometry patterns in the presence of Alzheimer's disease and/or LATE neuropathologic changes

Post mortem MRI of cholinergic white matter pathways across neurodegenerative diseases

Cholinergic white matter pathway degeneration is central in Alzheimer's disease and Lewy body disease and can be assessed in vivo using magnetic resonance imaging proxies, but neuropathological validation is limited.

Tau‐associated neuronal loss in the intermediate nucleus of the human hypothalamus, a putative VLPO analog, in progressive supranuclear palsy and Alzheimer's disease

Sleep phenotypes differ in progressive supranuclear palsy (PSP) and Alzheimer's disease (AD). The human intermediate nucleus (IntN), a putative ventrolateral preoptic analog, promotes non‐rapid eye movement (NREM) sleep, but its disease‐specific vulnerability is unclear.

MARBLE: An in vivo MRI marker of limbic‐predominant age‐related TDP‐43 encephalopathy neuropathologic change (LATE‐NC)

Limbic‐predominant age‐related transactive response DNA binding protein 43 kDa encephalopathy neuropathologic change (LATE‐NC) is common in older adults, yet definitive diagnosis is only possible at autopsy.

Dopaminergic‐ and Cholinergic‐Related Structural MRI Patterns Across Cognitive Subtypes of Parkinson's Disease With Mild Cognitive Impairment

The dual syndrome hypothesis distinguishes frontostriatal and posterior cortical cognitive subtypes in Parkinson's disease with mild cognitive impairment (PD‐MCI), which are associated with distinct cognitive profiles and different risks of dementia.

TMEM106B is a selective modulator of TDP‐43 pathology in Alzheimer's disease

Co‐pathologies – including Lewy body, vascular, and TDP‐43 lesions – are common in Alzheimer's disease (AD), contributing to its clinical and pathological heterogeneity. Genetic risk factors may drive mixed pathology presentation, but their influence on the development of specific co‐pathologies remains unclear.

Subjective cognitive impairment: Towards early identification of Alzheimer disease (cid:2)