Open access
Tau‐associated neuronal loss in the intermediate nucleus of the human hypothalamus, a putative VLPO analog, in progressive supranuclear palsy and Alzheimer's disease
Shima Rastegar-Pouyani
Caroline Lew
F. Pereira
Abhijit Satpati
Ana Moreno Arnas
V. Paes
R. Leite
C. Suemoto
S. Spina
Gowoon Son
H. Heinsen
W. Seeley
Christine M. Walsh
Thomas C. Neylan
L. Grinberg
Medicine
Abstract
Sleep phenotypes differ in progressive supranuclear palsy (PSP) and Alzheimer's disease (AD). The human intermediate nucleus (IntN), a putative ventrolateral preoptic analog, promotes non‐rapid eye movement (NREM) sleep, but its disease‐specific vulnerability is unclear.