Comprehensive Evaluation of Atherosclerotic Cardiovascular Disease Risk Predictors Across the Pooled Cohort Equations, Predicting Risk of Cardiovascular Disease Events, and an Expanded Model
Jul 2026· Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease· Vol 15· 0 citations· 46 references
Medicine
Abstract
Ten‐year atherosclerotic cardiovascular disease (ASCVD) risk prediction models include the pooled cohort equations (PCE) and the Predicting Risk of Cardiovascular Disease Events (PREVENT) models. We evaluated the relative contributions of predictors in these models, along with social determinants and emerging biomarkers.
We conducted a population-based study examining the associations of diabetes duration and prior cardiovascular disease (CVD) with subsequent cardiovascular events. We demonstrate that diabetes-even if ≥ 10 years in duration-now confers an increased risk of cardiovascular events that is relatively lower than that of pri...
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We assessed the association between cardiovascular disease (CVD) and cognitive decline in adults aged 50 years or older using pooled data from five multinational cohorts, quantified heterogeneity, and explored its potential sources.
Cardiovascular disease remains one of the leading causes of morbidity and mortality worldwide, representing a major global public health challenge [...].
A higher 10-year ASCVD risk was associated with faster global cognitive decline and greatest risk-linked decline occurred in the attention and delayed memory domains, suggesting AHA PREVENT may aid early identification of cognitive risk.
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