Aug 2026· The journal of prevention of Alzheimer's disease· Vol 13, pp. 100651· 1 citation· 60 references
Medicine
TL;DR
A higher 10-year ASCVD risk was associated with faster global cognitive decline and greatest risk-linked decline occurred in the attention and delayed memory domains, suggesting AHA PREVENT may aid early identification of cognitive risk.
Abstract
Highlights • A higher 10-year ASCVD risk was associated with faster global cognitive decline.• Greatest risk-linked decline occurred in the attention and delayed memory domains.• ASCVD risk via AHA PREVENT may aid early identification of cognitive risk.
We assessed the association between cardiovascular disease (CVD) and cognitive decline in adults aged 50 years or older using pooled data from five multinational cohorts, quantified heterogeneity, and explored its potential sources.
Current risk equations miss many cardiovascular events in people classified as low risk. Prediction is simultaneously advancing on two axes: broadening predictors toward molecular omics, and expanding outcomes toward earlier subclinical atherosclerosis and later heart failure.
Mounting evidence suggests beta amyloid (Aβ) is not the sole initiating driver of cognitive decline in Alzheimer's disease (AD). This study explores whether there is an association between cognitive decline over eight years and Aβ.
J. David, Isabella Torres, Evan Smith et al.· Brain and Behavior· 0 citations
To systematically evaluate the association between current statin use and global cognitive impairment in US older adults and examine potential variations across treatment intensity, duration, and specific cognitive domains to guide clinical cardiometabolic management.
Jia-Ying Ding, Jia-Ning Miao, Ling Zhang et al.· Journal of Internal Medicine· 0 citations
Prevalence of dementia is higher in low‐ and middle‐income countries (LMICs). However, longitudinal studies characterizing cognitive decline and its clinical and epidemiological predictors remain scarce in Brazil.
G. T. O. Engelmann, J. C. de Alvarenga, G. C. P. Moro et al.· Alzheimer's & Dementia· 0 citations
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