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D. Lloyd-Jones

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Open access Sep 2026

Social Determinants of Health in Early to Mid-Adulthood and Risk of Early-Onset Stroke.

BACKGROUND Despite increasing incidence of stroke among younger adults, the associations of social determinants of health (SDOH) and stroke among younger adults are not well known. This study investigates the associations between SDOH from early adulthood and stroke in a prospective longitudinal cohort. METHODS We st...

Nathaniel H. Fleming, C. Dintica, Alexander Arynchyn et al. · 0 citations
Open access Aug 2026

Predictive Utility of Coronary Artery Calcium Score Added to the PREVENT Atherosclerotic Cardiovascular Disease Equations.

Reclassification results support selective use of CAC in those with borderline to intermediate risk estimated by the PREVENT-ASCVD equations, and in some groups, did not change model discrimination and reclassification.

Xiao-Ning Huang, Lucia C. Petito, N. Allen et al. · 0 citations
Open access Jul 2026

Comprehensive Evaluation of Atherosclerotic Cardiovascular Disease Risk Predictors Across the Pooled Cohort Equations, Predicting Risk of Cardiovascular Disease Events, and an Expanded Model

Ten‐year atherosclerotic cardiovascular disease (ASCVD) risk prediction models include the pooled cohort equations (PCE) and the Predicting Risk of Cardiovascular Disease Events (PREVENT) models. We evaluated the relative contributions of predictors in these models, along with social determinants and emerging biomarker...

Yixin Zhang, Ernst J. Schaefer, Hiroaki Ikezaki et al. · 0 citations
Open access Aug 2026

Association between Cardiovascular-Kidney-Metabolic Health and Early Arterial Injury in Young Adults in the United States: The Future of Families – Cardiovascular Health Among Young Adults Study

Among young adults, more advanced CKM stage was associated with worse CVH, including greater evidence of early arterial injury, elucidate the need for earlier preventive efforts and population-level interventions to address upstream drivers of CKM health.

Vaishnavi Krishnan, H. Ning, D. Notterman et al. · 2 citations
Aug 2026

External Validation of the PREVENT Equations in a National Sample of US Adults.

The PREVENT equations accurately and precisely estimate the 10-year risk of CVD, ASCVD, and HF in a large sample of US adults and support the generalizability of the PREVENT equations to inform guideline-recommended risk assessment and preventive efforts.

Sadiya S. Khan, Y. Sang, Xiao-Ning Huang et al. · 0 citations

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