Skip to content

The C-index illusion: discrimination without calibration in published survival models

Jul 2026 · arXiv.org · Vol abs/2607.19526 · 0 citations · 22 references
Computer Science

TL;DR

Three published survival-ML models across three structurally distinct domains are reproduced and a direct test of whether metric choice inverts model preference does not reject, though with limited power given two to three models per domain; the failure mode is better characterized as misplaced confidence in a chosen model than as choosing the wrong one.

Abstract

Recent work has argued normatively, on synthetic data, that evaluating survival models by discrimination alone (concordance index) yields systematically misleading model comparisons, because the metric ignores calibration and time-dependent accuracy. Whether this matters for real, published, non-clinical models has not been tested. We reproduce three published survival-ML models across three structurally distinct domains -- hard-drive failure prediction, peer-to-peer credit default, and user disengagement on digital platforms -- validate our instrument against the anchor paper's own synthetic experiment, and test five pre-registered hypotheses under a Holm-corrected family-wise error rate. Three of five reject (though one pre-registered threshold clears by a narrow margin). A model reproducing the published literature's discrimination almost exactly (C = 0.9595 vs. 0.958 reported) fails a formal calibration test at p<0.001; a broad feature-ablation search finds no single attribute responsible for its discrimination, so the calibration failure is not a trivial shortcut artifact. A lender's estimated default risk is biased upward by roughly two percentage points, growing to nearly four in the riskiest segment, when loan prepayment is treated as non-informative censoring rather than a competing risk. A platform's churn model shows probability estimates that degrade with the horizon even as global discrimination stays within the pre-registered C-index band. A direct test of whether metric choice inverts model preference does not reject, though with limited power given two to three models per domain; the failure mode we document is better characterized as misplaced confidence in a chosen model than as choosing the wrong one. We release a pre-registered evaluation harness with full code and an annotated notebook, so these results can be verified independently and the audit extended.

View source

Similar papers

#machine learning Review Open access Oct 2014

Software development in startup companies: A systematic mapping study

The results indicate that software engineering work practices are chosen opportunistically, adapted and configured to provide value under the constrains imposed by the startup context.

Nicolò Paternoster, Carmine Giardino, M. Unterkalmsteiner et al. · 394 citations · ⚡54

Diffusion models as plug-and-play priors

The possibility of inferring high-dimensional data inference in a model that consists of a prior and an auxiliary differentiable constraint given some additional information is considered, thereby allowing a range of potential applications in adapting models to new domains and tasks.

Alexandros Graikos, Esmeralda S. Whitammer, N. Jojic et al. · 316 citations · ⚡15

Trajectory Balance: Improved Credit Assignment in GFlowNets

It is proved that any global minimizer of the trajectory balance objective can define a policy that samples exactly from the target distribution, and empirically demonstrate the benefits of the trajectories balance objective for GFlowNet convergence, diversity of generated samples, and robustness to long action sequenc...

Esmeralda S. Whitammer, Moksh Jain, Emmanuel Bengio et al. · 302 citations · ⚡60

KTO: Model Alignment as Prospect Theoretic Optimization

This work proposes a HALO that directly maximizes the utility of generations instead of maximizing the log-likelihood of preferences, and suggests that the best loss depends on the inductive biases most appropriate for a given setting, an oft-overlooked consideration.

Kawin Ethayarajh, Winnie Xu, Niklas Muennighoff et al. · 195 citations · ⚡28
#machine learning Review Open access Jun 2014

Why Early-Stage Software Startups Fail: A Behavioral Framework

This state-of-practice investigation was performed using a literature review followed by a multiple-case study approach and presents how inconsistency between managerial strategies and execution can lead to failure by means of a behavioral framework.

Carmine Giardino, Xiaofeng Wang, P. Abrahamsson · 175 citations · ⚡19

TabICLv2: A better, faster, scalable, and open tabular foundation model

TabICLv2 is introduced, a new state-of-the-art foundation model for regression and classification built on three pillars: a novel synthetic data generation engine designed for high pretraining diversity, various architectural innovations, and optimized pretraining protocols, notably replacing AdamW with the Muon optimi...

Jingang Qu, David Holzmüller, G. Varoquaux et al. · 159 citations · ⚡44

Related blog posts

Microsoft Research Blog Oct 12, 2026

Simulating student learning for better AI tutoring

StudentSim is a research system for evaluating and improving AI tutoring tools before they are tested with learners. It models how individuals may engage with tutors, giving feedback to improve tutor performance across subjects like chess, writing, and mathematics. The post Simulating student learning for better AI tutoring appeared first on Microsoft Research.

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.