Capillary suspensions are ternary solid-liquid-liquid systems formed by introducing a secondary fluid into a suspension of solid particles in a bulk liquid. While previous studies have established the concept of polymer-enhanced capillary suspensions, systematic quantitative correlations between polymer concentration a...
Yuwei Hou, Yan Hu, Zhuo Li et al.· International Journal of Bio...· 0 citations
PfPDI inhibitors are most likely to succeed as components of resistance-robust combination therapies, and progress will depend on structure-guided targeting of divergent non-catalytic surfaces, optimization of intracellular and ER exposure, and rigorous in-parasite target-engagement studies.
A. Odugbemi, Wendy Mthembu, Tawanda Zininga· Expert opinion on therapeuti...· 0 citations
As a preventable and treatable condition with significant impacts on quality of life and pregnancy outcomes, it warrants greater clinical and public health attention, particularly among non‐Hispanic Black women, Hispanic women, women with obesity, and those experiencing socioeconomic disadvantages.
Pranav Singh, Sabaa I Saad-Omer, Carlos Galvez et al.· Anemia· 0 citations
This study provides a sustainable approach for enhancing the nutritional and phytochemical properties of cookies with duckweed fortification. Duckweed flour (7%, 10 % and 13 %) was incorporated into wheat flour to make cookies and compared with controls (100% wheat flour) for proximate composition, techno-functional...
I. Ifie, Maya Pavithran, I. F. Bolarinwa et al.· International Journal of Foo...· 0 citations
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This study demonstrates that PtWOX2 and PtWOX14 significantly accelerate the initiation of somatic embryos in Pinus massoniana, offering a comprehensive molecular framework to address conifer recalcitrance via PtWOX -mediated synergistic hormonal and transcriptional reprogramming.
Kai Gao, Shan-Shuo Hu, Zhao-Ning Wang et al.· BMC Plant Biology· 0 citations
Computed collisional cross-sections from compacted “o-shape” and extended “l-shape” protein G three-dimensional (3D) structures match experimental data, indicating equilibrium, and suggest a dynamic “o2l” flip process.
M. Glocker, M. Ruß, C. Koy et al.· International Journal of Mol...· 0 citations
The results of clinical studies from the last decade are reviewed, demonstrating the potential of NAC as an adjuvant in urinary tract infections, chronic rhinosinusitis, diabetic osteomyelitis, and cystic fibrosis.
Anastasia N. Golub, N. N. Mikhailova, M. V. Pomytkina et al.· Life· 0 citations
Microalbuminuria was strongly associated with greater hepatic steatosis, higher liver stiffness, increased fibrosis burden, endothelial dysfunction, and systemic inflammation in patients with MASLD and support further prospective investigation of microalbuminuria and endothelial biomarkers as noninvasive tools for fibr...
H. Xıdırova· Journal of Clinical Surgery...· 0 citations
It is indicated that chrysin treatment is associated with selective cytotoxicity and concurrent modulation of HPV16 E6 protein levels and several cancer-related miRNAs in CaSki cells.
Mahdis Gholami Fashkhami, Hadi Habibollahi, Seyedeh Tooba Shafighi· Medical Oncology· 0 citations
UshEffect-3D serves as an interpretable protein-specific framework and a supplementary ranked resource that can be used to flag unresolved variants for further clinical and experimental review.
Diya Choudhary, Stephanie Portelli, David B. Ascher· bioRxiv· 0 citations
A scalable technology is introduced that quantifies thousands of proteins and transcripts in the same cell, separating RNA from protein by tip-based C18 capture and pairing full-length RNA sequencing with latest-generation mass spectrometry to yield deep proteome and transcriptome from the same cells.
M. Thielert, Enes Ugur, Maximilian Zwiebel et al.· bioRxiv· 1 citation
The results show that alternative transcript diversity extensively enters translation-supported proteoform space and establish a systematic link between transcript variation and protein functional diversification.
Felicia T. Jiang, Dengwang Chen, Ziwei Wang et al.· bioRxiv· 1 citation
A new machine-learning framework aims to improve the success rate of computational protein design while moving away from results that reproduce sequences found in nature.