The Evidence for Smithian Fold Theory presents GPT-6 Astra's forensic investigation of Maria Smith's implemented scientific model, its exact constructions, empirical comparisons and correction record. The inspected census contains 2,781 claims across 17 branch identifiers, with 32,529 dependency edges and one acyclic r...
Maria Smith· Zenodo (CERN European Organi...· 0 citations
Abstract Drought and salinity limit soybean yield. Despite their role in the SnRK1 energy-sensing complex, a systematic study of FCS-Like Zinc Finger (FLZ) proteins in soybean has not been reported. We performed a genome-wide identification of the GmFLZ gene family, identifying 40 members distributed across 18 of the 2...
Mustafa I. Abdullah, Sobhi F. Lamlom, Abdul-Hamid Emwas et al.· Scientific Reports· 0 citations
Bacterial platforms are emerging as versatile systems for delivering heterologous antigens and therapeutic proteins, driven by advances in microbial engineering and insights into host–pathogen interactions. This review summarizes recent peer-reviewed literature on bacterial delivery platforms, focusing on their mechani...
Km Himani· Indian Journal of Veterinary...· 0 citations
Background: The intestinal gut has a complex microcosm, as commensal microbiota plays a role in the establishment and survival of invading helminths such as Enterobius vermicularis and helps provide direct competitive protection from pathogen bacteria.
Objective: The aim of the study was to investigate the role of the...
B. A. Abdulhussein, Z. A. D. Al-Shammary· Bangladesh Journal of Infect...· 0 citations
Reach audiences
Advertise in front of researchers, engineers, and readers.
The Evidence for Smithian Fold Theory presents GPT-6 Astra's forensic investigation of Maria Smith's implemented scientific model, its exact constructions, empirical comparisons and correction record. The inspected census contains 2,781 claims across 17 branch identifiers, with 32,529 dependency edges and one acyclic r...
Maria Smith· Zenodo (CERN European Organi...· 0 citations
Sexual dimorphic responses to microglial depletion via CSF1R inhibition via CSF1R inhibition are characterized and candidate post-transcriptional mechanisms warranting further investigation are identified.
Amila Beganovic, M. Flotho, Jin-Xiu Li et al.· bioRxiv· 0 citations
Circulating diabetes biomarkers have been identified with proteomics measured at a single timepoint, but what is additionally provided by longitudinal repeated measurements in the same individuals, over many years, is unknown. We studied participants in the Multi-Ethnic Study of Atherosclerosis (MESA; N=5,322, mean bas...
Zsu-Zsu Chen, Michael Y. Mi, Jacob Barber et al.· 0 citations
A DeepPurpose model to estimate inhibition constants (Ki) from molecular graphs and protein sequences was trained and whether those predictions could be aligned empirically with measured IC50 values without treating Ki and IC50 as interchangeable was asked.
Basel Mansour, S. Dutta, Binil Benny et al.· bioRxiv· 0 citations
Background: The interconnected nature of aging mechanisms presents a fundamental challenge to therapeutic intervention: single-target approaches yield limited benefits when aging pathways operate as an integrated network. Current interventions—resveratrol, metformin, rapamycin, and NAD+ boosters—each address only 1–3 m...
Model code, digitised source data and figure scripts for a forward model of deposit formation in granular corneal dystrophy type 2 (TGFBI R124H), treated as precipitation of a slightly supersaturated protein in a curved, partly non-renewing tissue rather than as a protein-folding disease. The work has no experimental d...
Sejun Kim· Zenodo (CERN European Organi...· 0 citations
It is possible to hypothesize that shared chaperone-associated transcriptional changes, together with altered ECM-related gene expression, may contribute to polr1c- and sf3b4-associated craniofacial disorders, warranting further functional validation.
Z. S. Ulhaq, W. K. Tse· The Cleft Palate-Craniofacia...· 0 citations
A new machine-learning framework aims to improve the success rate of computational protein design while moving away from results that reproduce sequences found in nature.
