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1,360 papers
Delivering therapeutic macromolecules to defined cell populations in vivo remains a central unsolved problem in biomedicine. Proteins, nucleic acids and viral vectors are cleared by phagocytes, degraded by enzymes, blocked by endothelial and interstitial barriers, and trapped in acidifying endolysosomes. Pre-existing i...
Gamma-aminobutyric acid (GABA) technology is a promising biotechnology method for enhancing stress tolerance and nutritional quality in agricultural plants. Although tomato (Solanum lycopersicum) is a major vegetable crop consumed worldwide and is rich in vitamins, minerals, and antioxidants, tomato fruits naturally co...
The CRISPR-Cas9 system's gene-editing fidelity relies on the HNH nuclease domain's ability to hydrolyze DNA via metal-ion catalysis. While IscB-ωRNA variants offer advantages for viral delivery due to their small size, their editing efficiency is much lower than Cas9. The understanding of how HNH-domain dynamics and me...
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Reproducibility archive for the study “Adult heart failure molecular anchoring and functional mapping diverge across cardiac systems.” This v1.0.0 package contains original figure-generation scripts, derived figure-source tables, and final PNG/SVG exports for Main Figures 1–5 and Supplementary Figures S1–S8, together w...
CRISPR/Cas9-induced DNA double-strand breaks (DSBs) are widely used for genome engineering, yet their capacity to provoke sister chromatid exchange (SCE) and associated genome instability remains incompletely understood, in part because exchanges between identical sister chromatids leave no sequence change and are invi...
Imagine being able to find a particular spelling mistake in the enormous instruction manual of life and correct it. This is the basic idea behind one of the most exciting technologies in modern biology: CRISPR-Cas gene editing. Our DNA contains the genetic instructions that control how cells develop and function. Chang...
Dataset Description This repository contains the synthetic genomic workflow dataset generated and used for the experimental evaluation of the PRIVAGEN-SHIELD framework, “PRIVAGEN-SHIELD: Privacy-Preserving Genomic Anomaly Detection via Hierarchical Blockchain-Authenticated Merkle Trees and Local Differential Privacy.”...
Reproducibility archive for the study “Adult heart failure molecular anchoring and functional mapping diverge across cardiac systems.” This v1.0.1 package contains original figure-generation scripts, derived figure-source tables, and final PNG/SVG exports for Main Figures 1–5 and Supplementary Figures S1–S8, together w...
N 6 -methyladenosine (m 6 A) is the most abundant internal modification of eukaryotic mRNA and is dynamically regulated by three classes of proteins: writers, erasers, and readers. Writers deposit methylation marks, erasers confer reversibility, and readers translate these signals into specific regulatory outcome...
The CRISPR-Cas9 system's gene-editing fidelity relies on the HNH nuclease domain's ability to hydrolyze DNA via metal-ion catalysis. While IscB-ωRNA variants offer advantages for viral delivery due to their small size, their editing efficiency is much lower than Cas9. The understanding of how HNH-domain dynamics and me...
GPT-Lab
· gpt-lab.eu
Oct 8, 2026
Exploring how generative AI could make machine vision more accessible to businesses. The post GenEye in a Box: Making Machine Vision Something You Can Just Ask For appeared first on GPT-Lab.
A Blog post by Ai2 on Hugging Face
A Blog post by ServiceNow-AI on Hugging Face
“InstructMesh” can generate designs for everyday objects that are easy to edit and fabricate for both experts and newcomers to 3D modeling.
Proof of concept for watermarking AI-generated proteins while preserving biological function.
Algorithms & Theory
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