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gene editing

1,414 papers

#artificial intelligence Open access Sep 2026

The Post-Economic Human: Artificial Intelligence, Ontological Displacement, and the Ideological Foundations of Future Conflict

Artificial intelligence is usually analysed as a productivity technology, a labour-market shock, or a governance problem. This article argues that its deeper political significance may arise from a fourth channel: ontological displacement. Ontological displacement occurs when a technology weakens the socially recognise...

Kwan Hong TAN · 0 citations
#gene editing Review Open access Sep 2026

Trichoderma specialized metabolites in biocontrol: gene-metabolite links, ecological functions, and translational bottlenecks.

Trichoderma spp. produce a diverse repertoire of metabolites with specific activities that contribute to biocontrol through direct antagonism, ecological signalling, and modulation of plant responses. However, current knowledge remains uneven: many metabolites are chemically described, whereas fewer are supported by ro...

Mario Riolo, Santa Olga Cacciola · 1 citation
#gene editing Open access Sep 2026

Parallel Optimization of Gene Editing

This paper explores the concept and potential of parallel gene editing for rapid optimization and adaptation of complex biological systems. The core idea is to leverage the inherent parallelism offered by technologies like CRISPR-Cas9 to simultaneously modify multiple genomic copies. This is then coupled with optimizat...

Jincheng Zhang · 0 citations
#gene editing Open access Sep 2026

Parallel Optimization of Gene Editing

This paper explores the concept and potential of parallel gene editing for rapid optimization and adaptation of complex biological systems. The core idea is to leverage the inherent parallelism offered by technologies like CRISPR-Cas9 to simultaneously modify multiple genomic copies. This is then coupled with optimizat...

Jincheng Zhang · 0 citations
#gene editing Open access Sep 2026

Patenting Genome Editing Technologies and its Impact on Access to Human Cellular and Gene Therapeutic Products in India

India has high burden of rare and genetic diseases and large underserved patient population. In recent years cellular and gene therapeutic products incorporating genome editing technologies have transitioned from laboratory to commercially approved curative therapies. These therapies raising hope for millions of patien...

Krishnendu Roy Sarkar · 0 citations
#gene editing Open access Sep 2026

Patenting Genome Editing Technologies and its Impact on Access to Human Cellular and Gene Therapeutic Products in India

India has high burden of rare and genetic diseases and large underserved patient population. In recent years cellular and gene therapeutic products incorporating genome editing technologies have transitioned from laboratory to commercially approved curative therapies. These therapies raising hope for millions of patien...

Krishnendu Roy Sarkar · 0 citations
#gene editing Sep 2026

Knockout of SfVipR2 confers Vip3Aa resistance in Spodoptera frugiperda with evidence of genetic complementation among non-allelic mutations of SfVipR1, SfVipR2, and SfCHS2.

It is confirmed that knockout of SfVipR2 using CRISPR/Cas9 gene editing also confers high-level, recessive resistance to Vip3Aa, indicating a substantial resistance risk in S. frugiperda and underscoring the need for resistance management tactics.

Xin-Ru Pang, Zheng Zhang, Duo Qin et al. · 0 citations
#gene editing Review Open access Aug 2026

Epigenetic strategies for fetal hemoglobin induction in sickle cell disease.

This review discusses medicinal chemistry approaches primarily targeting HDAC1/2, LSD1, and DNMT1, with emphasis on inhibitor classes, binding mechanisms, structural features, preclinical evidence, and translational limitations, and how a better understanding of γ-globin repression may guide the development of safer an...

Mateus Mello de Souza, A. R. Pavan, Victor Gabriel de Faria Pastre et al. · 0 citations
#gene editing Review Open access Aug 2026

Research on the Regulation of RNA by Traditional Chinese Medicine to Alleviate Chemotherapy Side Effects

This article systematically reviews the research progress of how TCM active ingredients reduce chemotherapy side effects by regulating specific RNA molecules and regulating related signaling pathways, including protecting bone marrow hematopoiesis, reducing gastrointestinal toxicity and relieving neurotoxicity and the...

Zi-Xi Di · 0 citations
#gene editing Review Open access Aug 2026

Mutational Landscape and Regulatory Network Analysis of TP53 and FOXA1 in Prostate Cancer

TP53 and FOXA1 mutations, observed in primary and metastatic castration-resistant prostate cancer, were associated with aggressive disease phenotypes and potential therapeutic resistance, and these findings highlight TP53 and FOXA1 as promising biomarkers and potential therapeutic targets in prostate cancer.

Shrijee Lakshkar, Pratha Tiwari, Heenal Bhatt et al. · 0 citations
#gene editing Open access Aug 2026

The Technosapien Temptation in AI, Genetic Engineering, and Mars Colonization

The public Christian theologian needs to assess the threats and promises of technosapienism in light of God’s promises that through sanctification the authors can become Christlike, living the holy life on Earth as well as in the future resurrection.

Ted Peters · 0 citations

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Google DeepMind Blog Sep 30, 2026

Introducing SynthID Bio

Proof of concept for watermarking AI-generated proteins while preserving biological function.

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