Content of image described in text. Summary Genetic management of threatened species to reduce extinction risk is sometimes considered controversial, with earlier surveys demonstrating that the general public are more cautious about genetic management than about some other conservation interventions including killing f...
K. Zander, P. Sunnucks, C. Hogg et al.· Bird conservation internatio...· 0 citations
Carbapenem-resistant Klebsiella pneumoniae (CRKP) has become a substantial public health threat worldwide. This trend is undoubtedly exacerbated by biofilm formation, which is closely related to bacterial virulence. Small RNAs (sRNAs) are post-transcriptional regulators of many biological processes in bacteria, includi...
Na Du, Min Yang, Yong-Shi Zhao et al.· Microorganisms· 0 citations
Highly efficient tissue culture and transformation systems are indispensable for micropropagation, the molecular studies of secondary metabolism, the biotechnological enhancement of bioactive compounds, and genome editing in plants. Solanum americanum is a diploid species with both vegetable and medicinal value, yet re...
This study uses giant unilamellar vesicles mimicking the endosomal membrane to directly visualize the interaction and membrane disruptions caused by two model LNPs constituted by two different ionizable lipids, establishing a cell-free platform for dissecting individual sub-steps of endosomal escape.
functional-standard-atlas: attenuation-corrected, territory-resolved benchmarking of variant effect predictors against saturation genome editing Software and frozen data underlying the manuscript "Measurement reliability bounds functional benchmarks and relocates where variant effect prediction fails" (N. Zhang). WHAT...
Ningyi Zhang· Zenodo (CERN European Organi...· 0 citations
The results reveal a unique human mechanism of disease and offer therapeutic insight for this inflammasomopathy and CRISPR editing of human CD34+ hematopoietic stem and progenitor cells (HSPCs) led to very efficient and persistent gene deletion in vivo.
Tian-Li Xiao, J. R. Brewer, Maximillian J. Carlino et al.· Journal of Clinical Investig...· 0 citations
It was concluded that these technologies surpass the biological efficiency thresholds necessary to halt retinal degeneration and are established not as universal solutions, but as complementary tools whose selection depends strictly on the genetic architecture of the pathology.
The study confirms the usefulness of the rpoC1 gene region for identifying A.hydridus and provides additional molecular data for species, which may support plant identification and biodiversity documentation of Amaranthus based products.
K. Abdulkareem, Precious Ayantayo, Shehu Tsoho et al.· FUDMA Journal of Sciences· 0 citations
Renal fibrosis is the irreversible pathological core of chronic kidney disease (CKD). Current treatments can slow disease progression, but cannot cure it. Epigenetic regulatory mechanisms provide new perspectives for understanding and intervening in this process. This review summarizes the core epigenetic regulatory ne...
The year 2025 marked significant advances in autologous cellular therapy for melanoma and solid tumors, building on landmark regulatory approvals in 2024. Lifileucel, the first Food and Drug Administration‐approved tumor‐infiltrating lymphocyte (TIL) therapy for advanced melanoma, demonstrated durable efficacy in the 5...
Consumer acceptance of insulin produced via a gene-edited production system compared with insulin produced using conventional genetically modified microbial methods is examined to suggest that affordability plays a more influential role than perceived safety in shaping consumer acceptance of emerging biotechnology-base...
Nathan P. Kemper, B. McFadden· Agricultural and Resource Ec...· 0 citations
Colon cancer ranks among the most prevalent malignant tumors worldwide, with its incidence rising progressively year by year. The identification of novel research tool for therapeutic targets has thus become an urgent priority. Here, we constructed a CS•CBE integrative delivery and editing system via chitosan and cyt...
Min Li, Qian Ban, Da-Hai Liu et al.· ACS Omega· 0 citations
Exploring how generative AI could make machine vision more accessible to businesses. The post GenEye in a Box: Making Machine Vision Something You Can Just Ask For appeared first on GPT-Lab.
