This deposit contains the complete computational model and analysis code for a within-host study of autologous CCR5 gene-edited HIV cure. The work shows that the conversion of a patient's CD4 T cell pool to an HIV-resistant state is rate-limited by the turnover of the patient's own unedited cells rather than by any pro...
Mohammad Hamdallah· Zenodo (CERN European Organi...· 0 citations
SpectralKoopman This repository provides an implementation of the Spectral Koopman Approximation (SKA) method for stochastic reaction networks (SRNs). The code accompanies the manuscript: A spectral framework for revealing the hidden low-dimensional structure in stochastic reaction networks Ankit Gupta and Mustafa Kham...
Ankit Gupta· Zenodo (CERN European Organi...· 0 citations
The advent of CRISPR-Cas9 technology has revolutionized genome editing, enabling precise modifications to the human genome with unprecedented accuracy and sequence specificity. This review examines current mechanistic insights, translational advances, and clinical developments in gene editing, focusing on applications...
Abraham E. Ubhenin, F. Adamude, D. O. Ochalefu et al.· Nigerian Medical Journal· 0 citations
✨ Highlights Fork a session into a new writable copy. A local or imported session can be forked with its complete research history — conversation branches, Notebook records, artifact versions, literature, annotations, and private bookmarks all receive fresh identities. The source session is never altered, and imported...
Ewen, wen2zhou, Roxi et al.· Zenodo (CERN European Organi...· 0 citations
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SpectralKoopman This repository provides an implementation of the Spectral Koopman Approximation (SKA) method for stochastic reaction networks (SRNs). The code accompanies the manuscript: A spectral framework for revealing the hidden low-dimensional structure in stochastic reaction networks Ankit Gupta and Mustafa Kham...
Ankit Gupta· Zenodo (CERN European Organi...· 0 citations
The 33rd Fungal Genetics Conference was held from March 17th to the 22nd at the Asilomar Conference Center in Pacific Grove, California. The conference has been held at Asilomar 24 times since it began as the “Neurospora Information Conference” in 1961. Over meals at the large round tables, it is common for attendees t...
Abigail L. LaBella, Jessie MacAlpine, Marie‐Claire Harrison et al.· G3 Genes Genomes Genetics· 0 citations
This deposit contains the complete computational model and analysis code for a within-host study of autologous CCR5 gene-edited HIV cure. The work shows that the conversion of a patient's CD4 T cell pool to an HIV-resistant state is rate-limited by the turnover of the patient's own unedited cells rather than by any pro...
Mohammad Hamdallah· Zenodo (CERN European Organi...· 0 citations
Following the publication of the above article, an interested reader raised several comments on the study that required clarification on the part of the authors in order to confirm the reporting of certain of the results, and to make the paper fully comprehensible. First, in the Materials and methods section, the singl...
Hao Lin, Xin-Ran Cheng, Yang-Yang Ren et al.· International Journal of Mol...· 0 citations
The authors are grateful to the Editor of Oncology Reports for granting them this opportunity to publish a Corrigendum, and apologize to both the Editor and the readership for any inconvenience caused.
Le Hong, Gen Sun, Long Peng et al.· Oncology Report· 0 citations
Results indicate a possible link between transcriptional remodeling, RNA editing, and functional polarization of HCC-induced neutrophils, and provide an exploratory framework for investigating ADAR-regulated RNA editing in tumor-immune communication.
Qian Cao, Y. Duan· Journal of Biological Chemis...· 0 citations
This article systematically reviews the current research landscape of different ncRNAs in HNC at the molecular level and explores the challenges posed by heterogeneity in ncRNA therapy concerning delivery, target selection, and microenvironmental interference.
Xiao-Hang Zeng, Zi-Xia Wang, Jing-Yuan Cui et al.· Pharmacological Research· 0 citations
In vitro studies in an erythroid progenitor cell line and primary CD34+ cells demonstrated that the EPORW439* variant conferred a strong proliferative advantage to therapeutically modified erythroid progenitors, establishing a strategy to amplify the therapeutic benefit of otherwise limited in vivo HSPC gene editing fo...
Akshara Sakunthala Velmurugan, K. Paschoudi, Jack A. Queenan et al.· bioRxiv· 0 citations
Exploring how generative AI could make machine vision more accessible to businesses. The post GenEye in a Box: Making Machine Vision Something You Can Just Ask For appeared first on GPT-Lab.
