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gene editing

1,393 papers

#gene editing Review Open access Oct 2026

Combining Antiviral Therapy with Cancer Treatment in HBV-associated HCC: A Translational Approach.

This review examines the emerging concept of combining antiviral and anticancer strategies to improve clinical outcomes in HBV-HCC and highlights recent translational studies, clinical trials, and future directions that support a dual-modality approach.

M. Hashem, M. E. H. Kayesh, M. Kohara et al. · 0 citations
#gene editing Open access Oct 2026

Establishing a Transgenic Chicken Line Expressing Human Teriparatide Therapeutic Protein for Treating Osteoporosis

Osteoporosis is an emerging public health burden in India, affecting around 61 million people, while post-menopausal women accounting for 80% of the affected population. Teriparatide, a recombinant human parathyroid hormone (PTH 1–34), is commonly used for the treatment of severe osteoporosis. It has an anabolic effect...

Devender Singh, Sayan Kundu, Arpita Sahoo et al. · 0 citations
#gene editing Open access Oct 2026

Establishing a Transgenic Chicken Line Expressing Human Teriparatide Therapeutic Protein for Treating Osteoporosis

Osteoporosis is an emerging public health burden in India, affecting around 61 million people, while post-menopausal women accounting for 80% of the affected population. Teriparatide, a recombinant human parathyroid hormone (PTH 1–34), is commonly used for the treatment of severe osteoporosis. It has an anabolic effect...

Devender Singh, Sayan Kundu, Arpita Sahoo et al. · 0 citations
#gene editing Open access Oct 2026

Advances in Genome Editing and Genome Engineering Toolbox for Improving Livestock Health and Productivity

Introduction An ever-growing world population with increased income causes significant rises in the demand for livestock products such as dairy and meat. From 2020 to 2050, global demand for livestock products is projected to increase by 8%, and per capita protein requirements will rise by 38% (Komarek et al., 2021). I...

Sudeepta Kumar Panda, Gyanendra Singh · 0 citations
#gene editing Open access Oct 2026

Advances in Genome Editing and Genome Engineering Toolbox for Improving Livestock Health and Productivity

Introduction An ever-growing world population with increased income causes significant rises in the demand for livestock products such as dairy and meat. From 2020 to 2050, global demand for livestock products is projected to increase by 8%, and per capita protein requirements will rise by 38% (Komarek et al., 2021). I...

Sudeepta Kumar Panda, Gyanendra Singh · 0 citations
#gene editing Open access Oct 2026

CRISPR/Cas9-Mediated MSTN Knockout Alters Muscle Proteome and MSTN–ACVR2B Interaction in Buffalo Myoblasts

Myostatin (MSTN) is a potent negative regulator of skeletal muscle growth and differentiation. Buffalo myoblasts were isolated from the longissimus dorsi muscle and characterized by binucleate morphology and Pax7/myosin immunostaining. Myoblasts were nucleofected with MSTN guide RNA and Cas9, and three independently de...

Meeti Punetha, Sristi Bhatia, Bhavya Magoo et al. · 0 citations
#gene editing Open access Oct 2026

Integration of MOET and CRISPR/Cas9 RNP electroporation for MSTN genome editing in caprine zygotes

Myostatin (MSTN) is a key negative regulator of skeletal muscle growth and an important candidate gene for genetic improvement of economically relevant livestock traits. CRISPR/Cas9-mediated genome editing using ribonucleoprotein (RNP) delivery offers a precise approach for targeted MSTN modification in caprine embryos...

SHIVA PRATAP SINGH, Juhi Pathak, Manisha Pathak et al. · 0 citations
#gene editing Open access Oct 2026

Integration of MOET and CRISPR/Cas9 RNP electroporation for MSTN genome editing in caprine zygotes

Myostatin (MSTN) is a key negative regulator of skeletal muscle growth and an important candidate gene for genetic improvement of economically relevant livestock traits. CRISPR/Cas9-mediated genome editing using ribonucleoprotein (RNP) delivery offers a precise approach for targeted MSTN modification in caprine embryos...

SHIVA PRATAP SINGH, Juhi Pathak, Manisha Pathak et al. · 0 citations
#gene editing Open access Oct 2026

CRISPR/Cas9-Mediated MSTN Knockout Alters Muscle Proteome and MSTN–ACVR2B Interaction in Buffalo Myoblasts

Myostatin (MSTN) is a potent negative regulator of skeletal muscle growth and differentiation. Buffalo myoblasts were isolated from the longissimus dorsi muscle and characterized by binucleate morphology and Pax7/myosin immunostaining. Myoblasts were nucleofected with MSTN guide RNA and Cas9, and three independently de...

Meeti Punetha, Sristi Bhatia, Bhavya Magoo et al. · 0 citations
#gene editing Open access Oct 2026

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Adoptive transfer of proinflammatory myeloid cells enhances antitumor T‐cell responses and limits tumor growth in murine models. Previous work identified transcription factors NF‐κB p50 and STAT6 as key regulators whose inactivation enhances the inflammatory potential of murine myeloid cells. Herein, we translate murin...

Theresa Barberi, Alan D. Friedman · 0 citations
#gene editing Open access Oct 2026

Evolution of Stem Cell Therapy: From Embroyic and Adult Stem Cells to IPSCS in Disease Modelling, Cell Replacement and Precision Therapeutics

ABSTRACT Over recent years, stem cell therapy has transitioned from a potentially viable approach to an actual method of tissue repair and regeneration. This review highlights advances in the study of stem cell biology, their classification, and application in medical practice. In particular, the use of different sourc...

Dr.A.L. T Kalyani, M. Akanksha, T. Thanuja · 0 citations
#gene editing Open access Oct 2026

Evolution of Stem Cell Therapy: From Embroyic and Adult Stem Cells to IPSCS in Disease Modelling, Cell Replacement and Precision Therapeutics

ABSTRACT Over recent years, stem cell therapy has transitioned from a potentially viable approach to an actual method of tissue repair and regeneration. This review highlights advances in the study of stem cell biology, their classification, and application in medical practice. In particular, the use of different sourc...

Dr.A.L. T Kalyani, M. Akanksha, T. Thanuja · 0 citations

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Google DeepMind Blog Sep 30, 2026

Introducing SynthID Bio

Proof of concept for watermarking AI-generated proteins while preserving biological function.

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