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gene editing

1,434 papers

#gene editing Open access Aug 2026

The Effect of Bacillus pumilus 3-19 Metalloproteinase Gene Knockout on the Expression of Minor Proteases of the Strain Degradome and Its PGP Properties

The Bacillus pumilus 3-19 strain exhibits increased secretion of various hydrolases, including proteases, and is a promising plant growth-promoting (PGP) agent, and a deletion mutant of B. pumilus 3-19 with an inactivated mprBp gene was obtained.

D. I. Khasanov, N. Rudakova, I. Danilova et al. · 0 citations
#gene editing Open access Aug 2026

OsRAD23a negatively regulates salt tolerance and phosphorus uptake in rice

It is shown that the RAD23a regulates differential growth, salt response and Pi uptake in rice in a domain-specific manner supporting the moonlighting roles of RAD23a in salt tolerance and phosphorus-dependent shoot growth.

Shohei Oguro, Bilal Ahmad, J. S. Dharni et al. · 0 citations
#gene editing Open access Aug 2026

Transcriptomic and Physiological Profiling of Enhanced Drought Tolerance in a Gamma-Ray-Induced Colored Wheat Mutant

P phenotypic, physiological, and transcriptomic analyses were integrated to elucidate the drought adaptation mechanisms of a gamma-ray-induced mutant wheat line, PL6, alongside its wild-type parent, PL1, demonstrating an effective analytical framework for selection of high-confidence transcripts.

M. Hong, Ryu Jeong Kim, So Jin Park et al. · 0 citations
#gene editing Dataset Open access Aug 2026

Support data for: Synthesis cost is a hidden driver of convergent amino acid composition in plastid ribosomal proteins

Supporting data for the manuscript: Chaudhari et al., Synthesis cost is a hidden driver of convergent amino acid composition in plastid ribosomal proteins. List of contents:Data S1 Sequence alignments of all surveyed plastid and nuclear genes in Orobanchaceae, Geraniaceae, Fabaceae, and Caryophyllaceae. These genes inc...

Arnav Chaudhari, Palash Sethi, Yvemirca Vilbrun et al. · 0 citations
#gene editing Review Open access Aug 2026

GENETIC DISORDERS Molecular Mechanisms, Diagnostic Evolution, Precision Therapeutics and Future Directions: A Narrative Review

Genetic Disorders: Molecular Mechanisms, Diagnostic Evolution, Precision Therapeutics and Future Directions Description Genetic Disorders: Molecular Mechanisms, Diagnostic Evolution, Precision Therapeutics and Future Directions is a comprehensive narrative review examining the current understanding and rapidly evolving...

Dr.Zeeshan Qaiser · 0 citations
#gene editing Review Open access Aug 2026

The Technical System, Clinical Application and Future Prospects of Pluripotent Stem Cells (ESC/iPSC) Mediated Nerve Regeneration

The article traces the trend of directed differentiation technologies evolving from two-dimensional culture to three-dimensional organoids and details their practical applications in diseases such as stroke, Alzheimer's disease, and spinal cord injury—particularly in spinal cord injury models, where transplanted cells...

Dai-Yi Yang · 0 citations
#gene editing Open access Aug 2026

Knockout and re-expression system for mutant analysis in primary mouse T cells

The knockout and re-expression platform provides a useful gene editing tool for primary T cells in fundamental research and immunotherapy development and can be used to generate gene-edited primary T cells for in vivo studies, such as the quantification of anti-tumor responses.

Vasileios Morfos, M. Frie, Daniel Peschkov et al. · 0 citations
#gene editing Open access Aug 2026

Application of AI-Designed OpenCRISPR-1 for Highly Efficient Gene Editing in Soybean and Nicotiana benthamiana

The results demonstrate that the AI-designed OpenCRISPR-1 system is a highly active and versatile nuclease for dicot genome engineering, offering a powerful, commercially unencumbered tool to accelerate global crop trait improvement.

Cuong X. Nguyen, P. Do, Thu Minh Tran · 0 citations
#gene editing Open access Aug 2026

Development and Application of Adenine Base Editors for Precision Gene Therapy

CRISPR-Cas technology has revolutionized functional genomics, and gene therapy by enabling precise and programmable manipulation of the genome. Early CRISPR-Cas nucleases relied on the generation of double-strand breaks (DSBs) to disrupt genes or introduce exogenous DNA. More recently, the development of base editors a...

Jenny Gao · 0 citations
#gene editing Open access Aug 2026

TheDongLab/AI2AMP-PD: AI2AMP-PD v1.0

This is the first public release of the analysis code accompanying the manuscript "Differential expression and machine-learning classification of Parkinson's disease using AMP-PD RNA-seq data" (Hu R, Dong X, et al.). Overview Analysis pipeline for RNA-seq–based differential expression (DE) and machine-learning (ML) cla...

TheDongLab · 0 citations
#gene editing Editorial Open access Aug 2026

Editorial: Harnessing genomics to revolutionize plant disease management and preservation of soil biodiversity

The articles collected in this Research Topic highlight the growing integration of genomics and microbial ecology in advancing plant disease management and soil health. Together, they demonstrate how molecular approaches can reveal the mechanisms that shape microbial communities, uncover the genetic basis of pathogen v...

Setu Bazie Tagele, Assefa Sintayehu Kassa, Shimeles Tilahun et al. · 0 citations
#gene editing Open access Aug 2026

TheDongLab/AI2AMP-PD: AI2AMP-PD v1.0

This is the first public release of the analysis code accompanying the manuscript "Differential expression and machine-learning classification of Parkinson's disease using AMP-PD RNA-seq data" (Hu R, Dong X, et al.). Overview Analysis pipeline for RNA-seq–based differential expression (DE) and machine-learning (ML) cla...

TheDongLab · 0 citations

From tech blogs

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Google DeepMind Blog Sep 30, 2026

Introducing SynthID Bio

Proof of concept for watermarking AI-generated proteins while preserving biological function.

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