Sep 2026
Disrupted PQBP1-HNRNPU-LINE-1 axis underlies aberrant neurodevelopment in renpenning syndrome.
Jin-Yu Zhang, Wen-Zheng Qu, Xue-Jun Cheng et al.
· Molecular Psychiatry · 0 citations
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AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
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HOPX regulates the development and lineage progression of human stem cell-derived outer radial glia-like cells
Using CRISPR-Cas9 gene editing in human pluripotent stem cells, HOPX is identified as an important regulator of oRG-like cell maintenance and the neurogenic-gliogenic balance, providing insight into the molecular programs governing human neural progenitor expansion.
Xiao-Xue Dong, Wendy W. Y. Choi, Mai Ahmed et al.
· Stem Cell Reports · 0 citations
Open access
Aug 2026
Long-read proteogenomic atlas of human neuronal differentiation reveals isoform diversity informing neurodevelopmental risk mechanisms
Deep long-read RNA sequencing and proteomics in induced pluripotent stem cell-derived cortical neurons is integrated to generate a high-resolution proteogenomic atlas of human neuron development, uncovering thousands of novel isoforms and revealing dynamic splicing changes in autism risk genes.
N. Xu, Katherine M. Rynard, E. Radley et al.
· Nature Communications · 1 citation