Malnourished children are susceptible to an increased risk of mortality owing to impaired immune functions. However, the underlying mechanism of altered immune functions and its interaction with malnutrition is poorly understood. This study investigates the immune function and evaluates the effect of a particular nutri...
Zannatun Noor, M. Hasan, Md. Amran Gazi et al.· Scandinavian Journal of Immu...· 6 citations
Background and objective Serological screening with a confirmation through biopsy has improved the understanding of coeliac disease (CD) epidemiology worldwide. Prevalence of CD in Bangladesh is not yet explored and therefore, we aimed to assess the seroprevalence of CD in slum-dwelling malnourished children and adults...
Md. Amran Gazi, Subhasish Das, M. Mahfuz et al.· BMJ Open Gastroenterology· 4 citations
Growth in young children is controlled through the release of several hormonal signals, which are affected by diet, infection, and other exposures. Stunting is clearly a growth disorder, yet limited evidence exists documenting the association of different growth biomarkers with child stunting. This study explored the a...
Muttaquina Hossain, B. Nahar, Md Ahshanul Haque et al.· Nutrients· 25 citations· ⚡1
Abstract. Chronic exposure to infectious agents results in environmental enteric dysfunction—a significant contributor to childhood stunting. Low plasma tryptophan (TRP), increased kynurenine (KYN), and KYN–TRP (KT) ratio are associated with infections and chronic immune activation. We postulated that both these condit...
Md. Amran Gazi, Subhasish Das, M. A. Siddique et al.· American Journal of Tropical...· 26 citations· ⚡1
Background Because Helicobacter pylori (H. pylori) infection and Environmental Enteric Dysfunction (EED) follow a similar mode of transmission, there can be a complex interplay between H. pylori infection and EED, both of which can influence childhood growth. We sought to investigate the factors associated with H. pylo...
S. M. Fahim, Subhasish Das, Md. Amran Gazi et al.· PLoS Neglected Tropical Dise...· 18 citations
Escherichia coli (E. coli) pathotypes are the most common cause of diarrhea, especially in developing countries. Environmental Enteric Dysfunction (EED) is presumed to be the result of infection with one or more pathotypes and can affect intestinal health and childhood growth. We sought to investigate the association o...
Md. Amran Gazi, M. Alam, S. M. Fahim et al.· Frontiers in Cellular and In...· 19 citations· ⚡2
Dysregulations in the mammalian target of rapamycin (mTOR) pathway are associated with several human anomalies. We aimed to elucidate possible implications for potential aberrations in the mTOR pathway with childhood malnutrition. We analyzed the activity of phospho-mTORC1 and the expressions of several mTOR pathway ge...
P. Palit, Md. Amran Gazi, Subhasish Das et al.· Nutrients· 5 citations
Fucosyltransferase 2 (FUT2) and 3 (FUT3) may influence host biological functions. We aim to assess the relationship between maternal and child FUT2 (Secretor) and FUT3 (Lewis) status with growth, body composition, gut health and histologic features in Bangladeshi children. We conducted a case–control study where secret...
Md. Amran Gazi, S. M. Fahim, M. Hasan et al.· Scientific Reports· 5 citations
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