Open access
Sep 2026
TNIK maintains a MYC-driven partial EMT state that supports proliferation and evasion of senescence in lung squamous cell carcinoma
Results implicate TNIK in the mechanisms linking epithelial-mesenchymal plasticity with proliferation and evasion of senescence and provide insights into future strategies for the clinical deployment of TNIK inhibitors in LUSC and other TNIK-dependent malignancies.
Mohaddase Hamidi, Kenneth O. Omolo, Korrey W. Hart et al.
· bioRxiv · 0 citations