Author

Karim Benabdellah

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#gene editing Open access Sep 2026

Nucleofection-Based CRISPR/Cas Delivery in Human T Cells for Immunotherapy Applications.

Electroporation-based delivery of CRISPR/Cas systems has emerged as a powerful and versatile approach for gene editing in primary human T cells, enabling efficient, transient, and nonviral modification while minimizing genomic integration risks. This chapter focuses on the principles and practical implementation of ele...

María Ortiz-Bueno, Alejandro Millán-López, K. Labun et al. · Methods in molecular biology · 0 citations

Review Open access Jul 2026

In vivo delivery strategies for therapeutic CRISPR genome editing

A comprehensive review of delivery modalities of CRISPR systems solely in vivo that underpin their therapeutic translation and outlines the remaining barriers to durable, tissue-selective, and broadly deployable CRISPR therapeutics is provided.

L. Martin, Jure Bohinc, Alessandra Recchia et al. · International Journal on Bio... · 0 citations